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Showing 1–2 of 2 results
Advanced filters: Author: Christoph Hoegenauer Clear advanced filters

  • Gut microbiota contribute to the pathogenesis of ulcerative colitis (UC), but the molecular mechanisms are still unclear. Here the authors show that colonic fluid from patients with UC is enriched for bacteria extracellular vesicles (BEV) coated with host IgA, and that these IgA-coated BEV may activate CD89+ immune cells to aggravate inflammation and colitis in mouse models.

    • Himadri B. Thapa
    • Christina A. Passegger
    • Stefan Schild
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-22

  • Archaea are an overlooked member of the human gut microbiota. This Perspective discusses key characteristics of archaea, their role in human health and physiology, and the clinical relevance of methanogenic archaea in the human gastrointestinal tract.

    • Christoph Hoegenauer
    • Heinz F. Hammer
    • Christine Moissl-Eichinger
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 19, P: 805-813