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Showing 1–7 of 7 results
Advanced filters: Author: Christopher B. Eiben Clear advanced filters

  • From 1980 to 2018, the levels of total and non-high-density lipoprotein cholesterol increased in low- and middle-income countries, especially in east and southeast Asia, and decreased in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe.

    • Cristina Taddei
    • Bin Zhou
    • Majid Ezzati
    ResearchOpen Access
    Nature
    Volume: 582, P: 73-77

  • Hydroxyglutarate synthase (HglS) converts 2-oxoadipate to D-2- hydroxyglutarate during lysine catabolism in bacteria. Here the authors use structural and biochemical approaches to show that HglS acts via successive decarboxylation and intramolecular hydroxylation and that homologous enzymes catalyze the final step of lysine catabolism in plants.

    • Mitchell G. Thompson
    • Jacquelyn M. Blake-Hedges
    • Jay D. Keasling
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • In Pseudoalteromonas rubra, an unclustered biosynthetic gene encodes a di-iron oxygenase-like enzyme that catalyzes regiospecific C–H activation and cyclization of prodigiosin, yet is unrelated to the Rieske oxygenases that produce other cyclized prodiginines.

    • Tristan de Rond
    • Parker Stow
    • Jay D Keasling
    Research
    Nature Chemical Biology
    Volume: 13, P: 1155-1157