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Showing 1–8 of 8 results
Advanced filters: Author: Christopher B. Rodell Clear advanced filters

  • The 2021 unprecedented Pacific Northwest heatwave broke temperature records by extraordinary amounts. Impacts included hundreds of deaths, mass-mortalities of marine life, increased wildfires, reduced crop and fruit yields, and river flooding.

    • Rachel H. White
    • Sam Anderson
    • Greg West
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-20

  • β-Cyclodextrin nanoparticles carrying an antagonist of the toll-like receptors TLR7 and TLR8 drive the M1 phenotype in tumour-associated macrophages and improve immunotherapy response rates in tumour mouse models when used with checkpoint blockade.

    • Christopher B. Rodell
    • Sean P. Arlauckas
    • Ralph Weissleder
    Research
    Nature Biomedical Engineering
    Volume: 2, P: 578-588

  • Engineering complex tissues requires high-throughput, three-dimensional patterning of materials and cells. A method to assemble small gel components using magnetic forces from encapsulated free radicals could be just the ticket.

    • Christopher B. Rodell
    • Jason A. Burdick
    News & Views
    Nature
    Volume: 514, P: 574-575

  • Nanoparticle albumin bound paclitaxel (nab-PTX) is widely used in the clinic to treat different cancers, but the effect of albumin on the distribution of the drug in tumours is not clear. Here the authors show that the accumulation of nab-PTX in tumours is affected by signalling molecules involved in nutrient uptake and processing, which could be reprogrammed to increase the drug’s efficacy.

    • Ran Li
    • Thomas S. C. Ng
    • Miles A. Miller
    Research
    Nature Nanotechnology
    Volume: 16, P: 830-839

  • Electrospinning is a useful method of biomaterial fabrication, but a lack of bioactivity in the final construct can limit their application as mimics for biological matrices. Here, the authors fabricate a degradable electrospun scaffold as an in vitro and in vivomimic of the extracellular matrix.

    • Ryan J. Wade
    • Ethan J. Bassin
    • Jason A. Burdick
    Research
    Nature Communications
    Volume: 6, P: 1-10