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Crystals with a light touch

Andrew Steane
Christopher Foot
News & Views27 Aug 1992
Nature

Volume: 358, P: 715-716
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Single cell RNA sequencing generates short reads from one end of a template, providing incomplete transcript coverage and limiting identification of diverse sequences such as antigen receptors. Here the authors combine long read nanopore sequencing with short read profiling of barcoded libraries to generate full-length antigen receptor sequences.

Mandeep Singh
Ghamdan Al-Eryani
Alexander Swarbrick
ResearchOpen Access16 Jul 2019
Nature Communications

Volume: 10, P: 1-13
Rifalazil Retains Activity Against Rifampin-resistant Mutants of Chlamydia pneumoniae

David M Rothstein
Robert J Suchland
Walter E Stamm
Research01 Aug 2008
The Journal of Antibiotics

Volume: 61, P: 489-495
Opposing T cell responses in experimental autoimmune encephalomyelitis

Activated clonally expanded CD4⁺ T cells display specificity to the myelin peptide MOG, whereas clonally expanded CD8⁺ T cells depend on T cell receptor recognition of unrelated surrogate peptides and have a regulatory function.

Naresha Saligrama
Fan Zhao
Mark M. Davis
Research07 Aug 2019
Nature

Volume: 572, P: 481-487
Simultaneous encoding of tactile information by three primate cortical areas

Miguel A. L. Nicolelis
Asif A. Ghazanfar
Jon H. Kaas
Research01 Nov 1998
Nature Neuroscience

Volume: 1, P: 621-630
A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease

Inglese et al. develop a predictive model that computes multi-regional statistical morpho-functional mesoscopic traits from T1-weighted magnetic resonance imaging scans. Their model reliably discriminates people with Alzheimer’s disease-related pathologies from those without.

Marianna Inglese
Neva Patel
Eric O. Aboagye
ResearchOpen Access20 Jun 2022
Communications Medicine

Volume: 2, P: 1-16
The dynamic relationships between the active and catabolic vitamin D metabolites, their ratios, and associations with PTH

Jonathan C. Y. Tang
Sarah Jackson
Christopher J. Washbourne
ResearchOpen Access06 May 2019
Scientific Reports

Volume: 9, P: 1-10

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Crystals with a light touch

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Rifalazil Retains Activity Against Rifampin-resistant Mutants of Chlamydia pneumoniae

Opposing T cell responses in experimental autoimmune encephalomyelitis

Simultaneous encoding of tactile information by three primate cortical areas

A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease

The dynamic relationships between the active and catabolic vitamin D metabolites, their ratios, and associations with PTH

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