As improvements continue to be made in medical care, so the number of immunocompromised patients increases, and invasive fungal infections caused byCryptococcus neoformans, Candida albicans and Aspergillus fumigatusare a particular problem for this group of patients. Here, the prospects for harnessing the fungal calcineurin pathway in the development of novel antifungals to tackle invasive fungal infections are discussed.
- William J. Steinbach
- Jennifer L. Reedy
- Joseph Heitman
