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Showing 1–2 of 2 results
Advanced filters: Author: Christopher N. Selverian Clear advanced filters

  • Krebs and colleagues identify multiple mAbs that recognize either the RBD or the NTD of SARS-CoV-2 spike protein that have potent cross-neutralizing activities against variants of concern. Combinatorial mAb cocktails have complementary effects on viral neutralization and Fc effector functions and can protect against SARS-CoV-2 escape mutants.

    • Vincent Dussupt
    • Rajeshwer S. Sankhala
    • Shelly J. Krebs
    ResearchOpen Access
    Nature Immunology
    Volume: 22, P: 1503-1514

  • Tecovirimat forces dimerization of the poxvirus phospholipase F13 blocking virus spread. Clinical monkeypox virus strains resistant to tecovirimat show mutations in the F13 dimer interface.

    • Riccardo Vernuccio
    • Alejandro Martínez León
    • Pablo Guardado-Calvo
    ResearchOpen Access
    Nature Microbiology
    Volume: 10, P: 734-748