Nature Search

Bioinformatics analysis of homologies between pathogen antigens, autoantigens and the CFTR cystic fibrosis protein: A role for immunoadsorption therapy?

Christopher Carter
ResearchOpen Access02 Dec 2010
Nature Precedings

P: 1
Epstein–Barr virus latent membrane protein inhibits human epithelial cell differentiation

Christopher W. Dawson
Alan B. Rickinson
Lawrence S. Young
Research19 Apr 1990
Nature

Volume: 344, P: 777-780
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein

Melanie G. Lee
Christopher J. Norbury
Paul Nurse
Research16 Jun 1988
Nature

Volume: 333, P: 676-679
Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

William C. Sha
Christopher A. Nelson
Dennis Y. Loh
Research15 Sept 1988
Nature

Volume: 335, P: 271-274
A positive feedback loop controls Toxoplasma chronic differentiation

Chronic differentiation in Toxoplasma gondii is controlled by a positive feedback loop between BFD1 and BFD2.

M. Haley Licon
Christopher J. Giuliano
Sebastian Lourido
Research20 Apr 2023
Nature Microbiology

Volume: 8, P: 889-904
Publisher Correction: A systems view of spliceosomal assembly and branchpoints with iCLIP

Michael Briese
Nejc Haberman
Jernej Ule
Amendments and Corrections05 May 2021
Nature Structural & Molecular Biology

Volume: 28, P: 455
A systems view of spliceosomal assembly and branchpoints with iCLIP

Mapping spliceosome engagement with pre-mRNAs using iCLIP reveals how the position and strength of branchpoints affect the crosslinking patterns of spliceosomal factors.

Michael Briese
Nejc Haberman
Jernej Ule
Research30 Sept 2019
Nature Structural & Molecular Biology

Volume: 26, P: 930-940
Tree-ring isotopes adjacent to Lake Superior reveal cold winter anomalies for the Great Lakes region of North America

Steven L. Voelker
S. -Y. Simon Wang
Avner Ayalon
ResearchOpen Access13 Mar 2019
Scientific Reports

Volume: 9, P: 1-10
Author Correction: A systems view of spliceosomal assembly and branchpoints with iCLIP

Michael Briese
Nejc Haberman
Jernej Ule
Amendments and Corrections08 Jul 2020
Nature Structural & Molecular Biology

Volume: 27, P: 768
A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

Astrocytes can have protective or detrimental effects on neurons during injury, but the molecular mechanisms that determine these different states are unresolved. Here the authors identify a pathway via neuronal EphB1 that induces neuroprotective signalling in astrocytes through ephrin-B1 mediated STAT3 activation, which is impaired in models of amyotrophic lateral sclerosis.

Giulia E. Tyzack
Claire E. Hall
András Lakatos
ResearchOpen Access27 Oct 2017
Nature Communications

Volume: 8, P: 1-17
Modulation of innate immunity by Toxoplasma gondii virulence effectors

The intracellular parasiteToxoplasma gondiican infect a range of hosts and occasionally causes serious disease in humans. In this Review, Hunter and Sibley summarize recent studies that implicate rhoptry kinases and a dense-granule protein as mediators of acute virulence in the mouse model. They also describe the complex interplay between these parasite effector proteins and the innate immune system.

Christopher A. Hunter
L. David Sibley
Reviews16 Oct 2012
Nature Reviews Microbiology

Volume: 10, P: 766-778
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice

Paterson and Yu et al. demonstrate that loss of the RNA alternative splicing factor RBFOX2 in the liver during a lipogenic diet leads to dysregulation of liver lipid and cholesterol homeostasis through a specific alternative splicing programme, which includes a splice switch of the high-density lipoprotein receptor gene Scarb1.

Helen A. B. Paterson
Sijia Yu
Santiago Vernia
ResearchOpen Access19 Dec 2022
Nature Metabolism

Volume: 4, P: 1812-1829
Mutational signatures of ionizing radiation in second malignancies

Ionizing radiation may induce irreparable DNA damage leading to cancer. Here, the authors identify a specific signature of mutations arising in patients exposed to ionizing radiation and suggest that radiation-induced tumorigenesis is associated with higher rates of genome-wide deletions and balanced inversions.

Sam Behjati
Gunes Gundem
Peter J. Campbell
ResearchOpen Access12 Sept 2016
Nature Communications

Volume: 7, P: 1-8
CRISPR-based functional profiling of the Toxoplasma gondii genome during acute murine infection

A genome-wide CRISPR-based screen of Toxoplasma gondii during mouse infection reveals previously uncharacterized factors contributing to parasite virulence.

Christopher J. Giuliano
Kenneth J. Wei
Sebastian Lourido
Research08 Jul 2024
Nature Microbiology

Volume: 9, P: 2323-2343
Lessons from non-canonical splicing

Advances in transcriptomics and analysis have identified thousands of previously unknown non-canonical splicing events. In this Review, the authors discuss the mechanisms and functions of these events and their roles in a variety of diseases. They explain how non-canonical splicing mechanisms can be targeted or exploited for therapeutic strategies.

Christopher R. Sibley
Lorea Blazquez
Jernej Ule
Reviews31 May 2016
Nature Reviews Genetics

Volume: 17, P: 407-421
Recursive splicing in long vertebrate genes

Highly conserved recursive splice sites are identified in vertebrates, particularly within long genes encoding proteins that are involved in neuronal development; analysis of the splicing mechanism reveals that such recursive splicing sites can be used to dictate different mRNA isoforms.

Christopher R. Sibley
Warren Emmett
Jernej Ule
Research13 May 2015
Nature

Volume: 521, P: 371-375
The natural history of Amblyomma maculatum sensu lato, a vector of Rickettsia parkeri rickettsiosis, in southern Arizona

Geoffrey E. Lynn
Taylor J. Ludwig
Tammi L. Johnson
ResearchOpen Access15 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

Nick Orr and colleagues report a genome-wide association study for male breast cancer. They identify a new susceptibility locus at RAD51B and examine association evidence for known female breast cancer loci in these cohorts.

Nick Orr
Alina Lemnrau
Anthony J Swerdlow
Research23 Sept 2012
Nature Genetics

Volume: 44, P: 1182-1184
Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities

Christopher J van der Gast
Alan W Walker
Kenneth D Bruce
ResearchOpen Access09 Dec 2010
The ISME Journal

Volume: 5, P: 780-791
A flexible microfluidic system for single-cell transcriptome profiling elucidates phased transcriptional regulators of cell cycle

Karen Davey
Daniel Wong
Christopher R. Sibley
ResearchOpen Access12 Apr 2021
Scientific Reports

Volume: 11, P: 1-13
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

Whole-genome sequencing of normal blood cells sampled from 241 adults is used to infer mosaic point mutations that are likely to have arisen during early embryogenesis, providing insight into how early cellular dynamics may affect adult tissues.

Young Seok Ju
Inigo Martincorena
Michael R. Stratton
Research22 Mar 2017
Nature

Volume: 543, P: 714-718
Mechanical stimuli activate gene expression via a cell envelope stress sensing pathway

Christine E. Harper
Wenyao Zhang
Christopher J. Hernandez
ResearchOpen Access26 Aug 2023
Scientific Reports

Volume: 13, P: 1-12
Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention

Leah Cuthbertson
Geraint B Rogers
Christopher J van der Gast
ResearchOpen Access10 Nov 2015
The ISME Journal

Volume: 10, P: 1081-1091
Species and Media Effects on Soil Carbon Dynamics in the Landscape

S. Christopher Marble
Stephen A. Prior
Patricia R. Knight
ResearchOpen Access03 May 2016
Scientific Reports

Volume: 6, P: 1-9
Multidecade Mortality and a Homolog of Hepatitis C Virus in Bald Eagles (Haliaeetus leucocephalus), the National Bird of the USA

Tony L. Goldberg
Samuel D. Sibley
Sean M. Strom
ResearchOpen Access18 Oct 2019
Scientific Reports

Volume: 9, P: 1-12
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

Boris Rogelj
Laura E. Easton
Jernej Ule
ResearchOpen Access28 Aug 2012
Scientific Reports

Volume: 2, P: 1-10
Administration of the D2 Dopamine Receptor Antagonist Sulpiride into the Shell, but not the Core, of the Nucleus Accumbens Attenuates Cocaine Priming-Induced Reinstatement of Drug Seeking

Sharon M Anderson
Heath D Schmidt
R Christopher Pierce
Research05 Oct 2005
Neuropsychopharmacology

Volume: 31, P: 1452-1461
Fragile X Messenger Ribonucleoprotein 1 (FMR1), a novel inhibitor of osteoblast/osteocyte differentiation, regulates bone formation, mass, and strength in young and aged male and female mice

Padmini Deosthale
Julián Balanta-Melo
Lilian I. Plotkin
ResearchOpen Access17 May 2023
Bone Research

Volume: 11, P: 1-14
Thermal conductance across harmonic-matched epitaxial Al-sapphire heterointerfaces

The mechanism of thermal transport at solid interfaces depends on many parameters in particular the quality of the interface. Here, the authors compare experimental and calculated thermal boundary conductance across high-quality harmonic-matched epitaxial Al-sapphire interfaces and find that elastic phonon processes dominate the ultra-clean interfaces.

Zhe Cheng
Yee Rui Koh
Samuel Graham
ResearchOpen Access24 Jun 2020
Communications Physics

Volume: 3, P: 1-8

Search

Bioinformatics analysis of homologies between pathogen antigens, autoantigens and the CFTR cystic fibrosis protein: A role for immunoadsorption therapy?

Epstein–Barr virus latent membrane protein inhibits human epithelial cell differentiation

Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

A positive feedback loop controls Toxoplasma chronic differentiation

Publisher Correction: A systems view of spliceosomal assembly and branchpoints with iCLIP

A systems view of spliceosomal assembly and branchpoints with iCLIP

Tree-ring isotopes adjacent to Lake Superior reveal cold winter anomalies for the Great Lakes region of North America

Author Correction: A systems view of spliceosomal assembly and branchpoints with iCLIP

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

Modulation of innate immunity by Toxoplasma gondii virulence effectors

Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice

Mutational signatures of ionizing radiation in second malignancies

CRISPR-based functional profiling of the Toxoplasma gondii genome during acute murine infection

Lessons from non-canonical splicing

Recursive splicing in long vertebrate genes

The natural history of Amblyomma maculatum sensu lato, a vector of Rickettsia parkeri rickettsiosis, in southern Arizona

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities

A flexible microfluidic system for single-cell transcriptome profiling elucidates phased transcriptional regulators of cell cycle

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

Mechanical stimuli activate gene expression via a cell envelope stress sensing pathway

Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention

Species and Media Effects on Soil Carbon Dynamics in the Landscape

Multidecade Mortality and a Homolog of Hepatitis C Virus in Bald Eagles (Haliaeetus leucocephalus), the National Bird of the USA

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

Administration of the D2 Dopamine Receptor Antagonist Sulpiride into the Shell, but not the Core, of the Nucleus Accumbens Attenuates Cocaine Priming-Induced Reinstatement of Drug Seeking

Fragile X Messenger Ribonucleoprotein 1 (FMR1), a novel inhibitor of osteoblast/osteocyte differentiation, regulates bone formation, mass, and strength in young and aged male and female mice

Thermal conductance across harmonic-matched epitaxial Al-sapphire heterointerfaces

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