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Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia

Functional divergence of CYP76AK subfamily, accompanied by oxidation variations at C-20, leads to diverse abietane-type diterpenoids in Salvia species. Enzyme activity loss contributes to this unique chemical diversity within the lineage.

Jiadong Hu
Shi Qiu
Wansheng Chen
ResearchOpen Access04 Aug 2023
Nature Communications

Volume: 14, P: 1-16
A large-scale chloroplast phylogeny of the Lamiaceae sheds new light on its subfamilial classification

Bo Li
Philip D. Cantino
Dian-Xiang Zhang
ResearchOpen Access17 Oct 2016
Scientific Reports

Volume: 6, P: 1-18
Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice

Peng-ju Yan
Zhao-xiang Ren
Xue-chu Zhen
Research22 Nov 2021
Acta Pharmacologica Sinica

Volume: 43, P: 1686-1698
Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury

Yong-Yue Gao
Zi-Huan Zhang
Chun-Hua Hang
ResearchOpen Access28 Aug 2018
Cell Death & Disease

Volume: 9, P: 1-17
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum

Guo-He Tan
Yuan-Yuan Liu
Zhi-Qi Xiong
ResearchOpen Access20 Oct 2017
Cell Research

Volume: 28, P: 90-110