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Showing 1–3 of 3 results
Advanced filters: Author: Claes Andréasson Clear advanced filters

  • Here the authors discover a dedicated ribosome-associated chaperone, Chp1, that assists in the challenging biogenesis of eukaryotic translation elongation factor 1A (eEF1A) by cotranslationally stabilizing the growing GTPase domain of eEF1A.

    • Melania Minoia
    • Jany Quintana-Cordero
    • Claes Andréasson
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • During aging, proteins are damaged and can misfold, compromising cellular viability. Here, Kohler et al. uncover how aging cells maintain fitness by redirecting the protein repair factor Hsp104 to the nucleus in response to metabolic cues.

    • Verena Kohler
    • Andreas Kohler
    • Sabrina Büttner
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20