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Showing 1–3 of 3 results
Advanced filters: Author: Claudia Abou-Ajram Clear advanced filters

  • Comparative Physicochemical Profiling (CPP), an interpretable machine learning algorithm, identifies physicochemical signatures of γ-secretase substrates, capturing features hidden in sequences and enabling proteome-wide prediction of substrate recognition.

    • Stephan Breimann
    • Frits Kamp
    • Harald Steiner
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • The introduction of α-synuclein into mouse models of Alzheimer's disease, either by intracerebral injection or transgenic overexpression, is found to inhibit the formation of hippocampal amyloid-β plaques.

    • Teresa Bachhuber
    • Natalie Katzmarski
    • Melanie Meyer-Luehmann
    Research
    Nature Medicine
    Volume: 21, P: 802-807