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Scientific Reports (2)
Nature Metabolism (2)

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Showing 1–4 of 4 results

Advanced filters: Author: Claudia Boldrini Clear advanced filters

Implementation of the asparaginase activity assessment technique for clinical use: experience of a Brazilian Center

Daiane Keller Cecconello
Ciliana Rechenmacher
Mariana Bohns Michalowski
ResearchOpen Access08 Dec 2020
Scientific Reports

Volume: 10, P: 1-6
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix

Targeting extracellular matrix (ECM) remodelling is a feasible avenue to prevent cancer aggressiveness and metastasis. In this study, Kay et al. show that metabolic flux in cancer-associated fibroblasts is coupled to enhanced proline synthesis by PYCR1 to support elevated production of collagen-rich ECM, thus contributing to cancer spreading.

Emily J. Kay
Karla Paterson
Sara Zanivan
ResearchOpen Access27 Jun 2022
Nature Metabolism

Volume: 4, P: 693-710
Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix

Emily J. Kay
Karla Paterson
Sara Zanivan
Amendments and CorrectionsOpen Access04 Aug 2022
Nature Metabolism

Volume: 4, P: 1084
Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets

Federica Ciregia
Marco Bugliani
Piero Marchetti
ResearchOpen Access18 Oct 2017
Scientific Reports

Volume: 7, P: 1-12

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