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Showing 1–7 of 7 results
Advanced filters: Author: Clemens Cabernard Clear advanced filters

  • In asymmetrically dividing cells, both spindle-dependent and spindle-independent cleavage furrow positioning pathways are involved in cytokinesis. Here the authors find that Survivin and the mitotic spindle are required to stabilize the position of the cleavage furrow and to complete cytokinesis in Drosophilaneuroblasts.

    • Michaela Roth
    • Chantal Roubinet
    • Clemens Cabernard
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-14

  • Chromatid segregation must be coordinated with cytokinesis to preserve genomic stability. Here the authors show that cells clear trailing chromatids from the cleavage site in a two-step cell elongation and demonstrate the role of myosin efflux in the second phase.

    • Emilie Montembault
    • Marie-Charlotte Claverie
    • Anne Royou
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15

  • Greenhouse gas emissions from biomass production and supply are increasing, mostly driven by international trade and with the greatest relative increase from biochemical industry, according to supply chain analysis of the bioeconomy.

    • Livia Cabernard
    • Clemens Schwingshackl
    • Stefanie Hellweg
    ResearchOpen Access
    Communications Earth & Environment
    Volume: 6, P: 1-14

  • The mitotic spindle plays a key part in determining the site of the cleavage furrow in dividing metazoan cells. But are other mechanisms also involved? Here evidence is provided for a spindle-independent pathway for furrow positioning that occurs during asymmetric divisions of Drosophila neuroblast cells. The pathway involves the Pins protein complex, which polarizes furrow-forming proteins to the basal cortex of the cell. This mechanism might also occur in other highly polarized cell types.

    • Clemens Cabernard
    • Kenneth E. Prehoda
    • Chris Q. Doe
    Research
    Nature
    Volume: 467, P: 91-94

  • Asymmetric cell division can generate daughter cells with cell size asymmetry, but the underlying mechanisms are not clear. Here the authors show that spatiotemporally controlled Myosin flows together with spindle asymmetry and positioning control cleavage furrow position and cortical expansion to establish physical asymmetry.

    • Chantal Roubinet
    • Anna Tsankova
    • Clemens Cabernard
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-16