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Showing 1–4 of 4 results
Advanced filters: Author: Cliff Rims Clear advanced filters

  • Boron is one of the main proxies for seawater-derived fluids in subduction zone volcanics and it is vital to characterise the location and concentration of boron in the oceanic lithosphere. Here the authors show that boron concentration in the mantle of downgoing slabs has been overestimated, because boron is strongly decoupled from water in the hydration process.

    • Andrew M. McCaig
    • Sofya S. Titarenko
    • Samuele Agostini
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10

  • The presence of antibodies to citrullinated protein antigens (ACPA) in peripheral blood represents a risk a state that is ‘at-risk’ for subsequent development of rheumatoid arthritis (RA). Here authors compare multiple molecular and immunological parameters in individuals who are ACPA positive without inflammatory arthritis, ACPA negative controls and patients diagnosed with ACPA positive early-stage RA to conclude that complex immunopathological processes are present in an ACPA positive state which may be targeted by future preventive approaches for RA.

    • Eddie A. James
    • V. Michael Holers
    • Kevin D. Deane
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12

  • Detection of antigen specificity in a blood sample is limited by low frequencies of individual clones. Here the authors develop an MHC class II combinatorial technique and apply it to immunophenotype human CD4+ T cells of multiple specificities in response to influenza vaccine in single blood samples.

    • Hannes Uchtenhagen
    • Cliff Rims
    • Eddie A. James
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12