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Showing 1–4 of 4 results
Advanced filters: Author: Collette C Parker Clear advanced filters

  • Imaging biomarkers (IBs) are used extensively in drug development and cancer research, but important differences exist between IBs and biospecimen-derived biomarkers. A tailored 'roadmap' is required for the development of new IBs to be used either in clinical research or for decision-making in healthcare. In this Consensus statement, a group of experts assembled by CRUK and the EORTC present 14 key recommendations for accelerating the clinical translation of IBs.

    • James P. B. O'Connor
    • Eric O. Aboagye
    • John C. Waterton
    ReviewsOpen Access
    Nature Reviews Clinical Oncology
    Volume: 14, P: 169-186

  • The astronomical event GW170817, detected in gravitational and electromagnetic waves, is used to determine the expansion rate of the Universe, which is consistent with and independent of existing measurements.

    • B. P. Abbott
    • R. Abbott
    • M. Serra-Ricart
    Research
    Nature
    Volume: 551, P: 85-88

  • Vallianatos et al. study the functional interactions of KMT2A and KDM5C, H3K4me enzymes known to be involved in neurodevelopmental disorders. Using genetic mouse models, neuronal structure analysis, neurobehavior, and epigenomic profiling, they demonstrate a mutually suppressive relationship between KMT2A and KDM5C during neurodevelopment.

    • Christina N. Vallianatos
    • Brynne Raines
    • Shigeki Iwase
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-14