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Showing 1–6 of 6 results
Advanced filters: Author: Connie M. Rhee Clear advanced filters
  • In the USA, mortality among patients with chronic kidney disease (CKD) and end-stage renal disease has declined over the past two decades. By contrast, new data indicate that the rate of CKD-associated deaths is increasing worldwide. This important finding highlights CKD as a major contributor to global morbidity and mortality.

    • Connie M. Rhee
    • Csaba P. Kovesdy
    News & Views
    Nature Reviews Nephrology
    Volume: 11, P: 199-200
  • Debate exists regarding the safety of metformin and the risk of metformin-associated lactic acidosis, particularly in the setting of kidney dysfunction. Data from two studies examining the interplay between metformin, acute kidney injury, and complications including lactic acidosis suggest that metformin should be used conservatively in patients with kidney dysfunction.

    • Connie M. Rhee
    • Kamyar Kalantar-Zadeh
    News & Views
    Nature Reviews Nephrology
    Volume: 13, P: 521-522
  • In this Review, the authors describe the potential benefits of partial versus radical nephrectomy for small renal cell carcinomas. They also discuss the risk ofde novokidney disease or progression of pre-existing chronic kidney disease after nephrectomy, the potential factors that might influence patient prognosis after this surgery, and the need for further research in this field.

    • Lin Li
    • Wei Ling Lau
    • Kamyar Kalantar-Zadeh
    Reviews
    Nature Reviews Nephrology
    Volume: 10, P: 135-145
  • Unpleasant symptoms — arising as a consequence of disease processes, comorbid conditions, therapeutics and lifestyle regimens — adversely affect the quality of life and life participation of patients with chronic kidney disease (CKD). This Perspective examines the concept and scope of symptom burden in CKD, theoretical frameworks and validated tools for symptom appraisal, and strategies with which to support patients actively through the identification and targeting of unpleasant symptoms.

    • Kamyar Kalantar-Zadeh
    • Mark B. Lockwood
    • Philip Kam-Tao Li
    Reviews
    Nature Reviews Nephrology
    Volume: 18, P: 185-198