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Showing 1–7 of 7 results
Advanced filters: Author: Corinne Crucifix Clear advanced filters
  • The structure of human TIP60-C uncovers a molecular machine that modifies and exchanges histones in the nucleosome, illustrating how vertebrates merge these activities, which are carried out by two independent assemblies in yeast.

    • Changqing Li
    • Ekaterina Smirnova
    • Adam Ben-Shem
    ResearchOpen Access
    Nature
    Volume: 635, P: 764-769
  • Pausing of RNA polymerase (RNAP) and transcription is regulated by the NusA and NusG transcription factors in bacteria. Here the authors provide structural evidence for how they interact with RNAP to carry out their pausing roles and also reveal functions for NusA and NusG in transcription termination.

    • Chengjin Zhu
    • Xieyang Guo
    • Albert Weixlbaumer
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12
  • Structural studies on the yeast transcription coactivator complex SAGA (Spt–Ada–Gcn5–acetyltransferase) provide insights into the mechanism of initiation of regulated transcription by this multiprotein complex, which is conserved among eukaryotes.

    • Gabor Papai
    • Alexandre Frechard
    • Adam Ben-Shem
    Research
    Nature
    Volume: 577, P: 711-716
  • Eukaryotic RNA polymerase I (Pol I) is responsible for the transcription of rRNA genes. Here the authors determine the cryo-EM structure of the Pol I-Rrn3 complex, providing insight into how Rrn3 stabilizes the monomeric initiation competent Pol I to drive pre-initiation complex formation.

    • Michael Pilsl
    • Corinne Crucifix
    • Patrick Schultz
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12