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Showing 1–6 of 6 results

Advanced filters: Author: Corinne E. Farrell Clear advanced filters

Genetic modifiers of APOE-ε4-associated cognitive decline

The APOE-ε4 allele is the strongest genetic risk factor for late-onset Alzheimer’s disease, but it is not deterministic. Here, the authors show that common genetic variation changes how APOE-ε4 influences cognition.

Alex G. Contreras
Skylar Walters
Timothy J. Hohman
ResearchOpen Access20 Feb 2026
Nature Communications

Volume: 17, P: 1-17
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

Anne Joutel
Christophe Corpechot
Elisabeth Tournier-Lasserve
Research24 Oct 1996
Nature

Volume: 383, P: 707-710
Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells

Corinne Capoulade
Brigitte Bressac-de Paillerets
Joëlle Wiels
Research01 Apr 1998
Oncogene

Volume: 16, P: 1603-1610
How asymmetric DNA replication achieves symmetrical fidelity

Genetic and genomic analyses show that S. cerevisiae DNA polymerase δ extrinsically proofreads for errors by polymerase ε and itself, and demonstrate that the symmetry of replication fidelity is achieved via coordinated efforts of intrinsic and extrinsic proofreading and DNA mismatch repair.

Zhi-Xiong Zhou
Scott A. Lujan
Thomas A. Kunkel
Research09 Dec 2021
Nature Structural & Molecular Biology

Volume: 28, P: 1020-1028
Classification of electrophysiological and morphological neuron types in the mouse visual cortex

Gouwens et al. established a morpho-electrical taxonomy of cell types for the mouse visual cortex via unsupervised clustering analysis of multiple quantitative features from 1,938 neurons available online at the Allen Cell Types Database.

Nathan W. Gouwens
Staci A. Sorensen
Christof Koch
Research17 Jun 2019
Nature Neuroscience

Volume: 22, P: 1182-1195
Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16