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Showing 1–2 of 2 results
Advanced filters: Author: Craig W. Gambogi Clear advanced filters
  • KRAB-zinc finger proteins repress retrotransposons and rapidly evolve in mammals. Here, the authors show that ERV insertions drive the emergence and diversification of new KZFP genes in mice, revealing a co-evolutionary mechanism between retroviruses and host repressors.

    • Melania Bruno
    • Sharaf M. Farhana
    • Todd S. Macfarlan
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • The computational prediction of protein allostery can guide experimental studies of protein function and cellular activity. Here, the authors develop a network-based method to detect allosteric coupling within proteins solely based on their structures, and set up a webserver for allostery prediction.

    • Jian Wang
    • Abha Jain
    • Nikolay V. Dokholyan
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13