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Journal of Human Genetics (2)
Gene Therapy (2)
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Showing 1–7 of 7 results

Advanced filters: Author: Cristina Fillat Clear advanced filters

A novel Wiskott-Aldrich syndrome protein (WASP) complex mutation identified in a WAS patient results in an aberrant product at the C-terminus from two transcripts with unusual polyA signals

Nuria Andreu
Maricruz García-Rodríguez
Cristina Fillat
Research01 Feb 2006
Journal of Human Genetics

Volume: 51, P: 92-97
Identification and characterization of a novel splice-site mutation in a patient with Wiskott-Aldrich syndrome

Nuria Andreu
Carmen Carreras
Cristina Fillat
Research18 Oct 2003
Journal of Human Genetics

Volume: 48, P: 590-593
Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies

mRNA translational control by CPEBs is reactivated in cancer. Here, the authors show that the insertion of CPE regulatory sequences in the 3′ UTR of the E1A viral gene induces oncoselectivity, with oncolytic potency in cancer cells but attenuated toxicity in normal tissues.

Eneko Villanueva
Pilar Navarro
Cristina Fillat
ResearchOpen Access16 Mar 2017
Nature Communications

Volume: 8, P: 1-9
MiR-93 is related to poor prognosis in pancreatic cancer and promotes tumor progression by targeting microtubule dynamics

Elena Vila-Navarro
Elena Fernandez-Castañer
Meritxell Gironella
ResearchOpen Access04 May 2020
Oncogenesis

Volume: 9, P: 1-14
E-cadherin contributes to the bystander effect of TK/GCV suicide therapy and enhances its antitumoral activity in pancreatic cancer models

L Garcia-Rodríguez
D Abate-Daga
C Fillat
Research19 Aug 2010
Gene Therapy

Volume: 18, P: 73-81
Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness

Eneko Villanueva
Maria Martí-Solano
Cristina Fillat
ResearchOpen Access09 Jun 2016
Scientific Reports

Volume: 6, P: 1-10
GCV modulates the antitumoural efficacy of a replicative adenovirus expressing the TAT8-TK as a late gene in a pancreatic tumour model

A Cascante
D Abate-Daga
C Fillat
Research23 Aug 2007
Gene Therapy

Volume: 14, P: 1471-1480