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Advanced filters: Author: Cristina M. Rodriguez-Quinteros Clear advanced filters

  • The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable to bind the actinmodulating kinase PAK2, triggers enhanced interferon responses.

    • Alexandre Laliberté
    • Caterina Prelli Bozzo
    • Frank Kirchhoff
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15