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Showing 1–6 of 6 results
Advanced filters: Author: Cyril Hanus Clear advanced filters
  • The implications of compartmentalization of protein synthesis and distribution within dendrites are not well understood. In this Opinion article, Hanus and Schuman discuss how the morphological complexity of dendrites and specialist regulatory mechanisms influence protein distribution and therefore the synaptic response to activity.

    • Cyril Hanus
    • Erin M. Schuman
    Reviews
    Nature Reviews Neuroscience
    Volume: 14, P: 638-648
  • The cells of many archaeal species display surface appendages that closely resemble bacterial Type IV pili (T4P). Here, Gaines et al. present a cryoEM structure of the archaeal adhesive pilus from Sulfolobus acidocaldarius, showing that the structure of the component subunit follows the canonical T4P blueprint but adopts three distinct conformations within the pilus.

    • Matthew C. Gaines
    • Shamphavi Sivabalasarma
    • Bertram Daum
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13
  • The model archaeon Sulfolobus acidocaldarius produces several protein filaments with specialised functions, including flagellum-like archaella, Aap pili, and adhesive threads. Here, the authors describe high-resolution structures and distinct glycosylation patterns for the three filaments, and present an integrated model of the filaments in the context of the S-layer.

    • Matthew C. Gaines
    • Michail N. Isupov
    • Bertram Daum
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16
  • Proteomes of distinct cell types in the brains of live mice are labeled and quantitated with a genetically encoded non-canonical amino-acid labeling method and click chemistry.

    • Beatriz Alvarez-Castelao
    • Christoph T Schanzenbächer
    • Erin M Schuman
    Research
    Nature Biotechnology
    Volume: 35, P: 1196-1201
  • Two assays reveal the birthplace of target proteins. In both, an antibody against a protein is used alongside an antibody that marks recent translation. The close proximity of both antibodies indicates the newly synthesized target protein.

    • Susanne tom Dieck
    • Lisa Kochen
    • Erin M Schuman
    Research
    Nature Methods
    Volume: 12, P: 411-414