Phagosome maturation is the process by which a particle-containing phagosome 'matures' through a series of increasingly acidic membrane-bound structures, becoming an acidic phagolysosome before fusing with lysosomes. The identification of a pathway for apoptotic cell-containing phagosomes reveals parallels and differences with receptor-mediated endocytosis.
- Jason M. Kinchen
- Kodi S. Ravichandran