Nature Search

Size Requirement of Polyinosinic Acid for DNA Synthesis, Viral Resistance, and Increased Survival of Leukaemic Mice

S. J. MOHR
D. G. BROWN
D. S. COFFEY
Correspondence20 Dec 1972
Nature New Biology

Volume: 240, P: 250-252
Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer

Dong Hoon Kwak
Jae-Sung Ryu
Young-Kug Choo
ResearchOpen Access28 Oct 2011
Experimental & Molecular Medicine

Volume: 43, P: 693-701
Plasma waves in the magnetosphere

D. J. Southwood
Reviews01 Jan 1978
Nature

Volume: 271, P: 309-316
JNK regulates muscle remodeling via myostatin/SMAD inhibition

Endurance and resistance exercise have different effects on skeletal muscle phenotype. Using mouse models and human subjects, the authors show that JNK/Smad2 signaling acts as molecular switch that when activated by resistance exercise leads to hypertrophy, and when inhibited promotes endurance adaptations in muscle.

Sarah J. Lessard
Tara L. MacDonald
Laurie J. Goodyear
ResearchOpen Access02 Aug 2018
Nature Communications

Volume: 9, P: 1-14
Structural and compositional dependence of the CdTe_xSe_1−x alloy layer photoactivity in CdTe-based solar cells

Using a CdTe_xSe_1−x alloy in CdTe solar cells leads to better performances. Here, Poplawsky et al. show that the photoactive properties of the alloy depend on its chemical composition and structural properties, and derive a phase diagram to further optimize alloy growth for photovoltaic devices.

Jonathan D. Poplawsky
Wei Guo
Yanfa Yan
ResearchOpen Access27 Jul 2016
Nature Communications

Volume: 7, P: 1-10
Two by two

D. H. Jennings
News & Views18 Oct 1974
Nature

Volume: 251, P: 574
Codon 89 polymorphism in the human 5α-reductase gene in primary breast cancer

A Scorilas
B Bharaj
E P Diamandis
ResearchOpen Access20 Mar 2001
British Journal of Cancer

Volume: 84, P: 760-767
An integrated map of genetic variation from 1,092 human genomes

This report from the 1000 Genomes Project describes the genomes of 1,092 individuals from 14 human populations, providing a resource for common and low-frequency variant analysis in individuals from diverse populations; hundreds of rare non-coding variants at conserved sites, such as motif-disrupting changes in transcription-factor-binding sites, can be found in each individual.

Gil A. McVean
David M. Altshuler (Co-Chair)
Gil A. McVean
ResearchOpen Access31 Oct 2012
Nature

Volume: 491, P: 56-65
Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel

1000 Genomes imputation can increase the power of genome-wide association studies to detect genetic variants associated with human traits and diseases. Here, the authors develop a method to integrate and analyse low-coverage sequence data and SNP array data, and show that it improves imputation performance.

Olivier Delaneau
Jonathan Marchini
Leena Peltonenz
Research13 Jun 2014
Nature Communications

Volume: 5, P: 1-9
Direct observations of energy transfer from resonant electrons to whistler-mode waves in magnetosheath of Earth

Excitation of whistler-mode waves by cyclotron instability is considered as the likely generation process of the waves. Here, the authors show direct observational evidence for locally ongoing secular energy transfer from the resonant electrons to the whistler-mode waves in Earth’s magnetosheath.

N. Kitamura
T. Amano
J. L. Burch
ResearchOpen Access28 Oct 2022
Nature Communications

Volume: 13, P: 1-12
Reduced expression of transforming growth factor-beta receptor type III in high stage neuroblastomas

A Iolascon
L Giordani
F Della Ragione
ResearchOpen Access22 Feb 2000
British Journal of Cancer

Volume: 82, P: 1171-1176
Remote detection and recording of atomic-scale spin dynamics

Scanning probe microscopy offers a creative way of fabricating structures by combining unmatched atomic-scale resolution and advanced functionalities. The authors utilize this technique to implement a novel spin chain configuration that, by means of a memory unit, can probe ultra-fast spin dynamics.

R. J. G. Elbertse
D. Coffey
A. F. Otte
ResearchOpen Access25 May 2020
Communications Physics

Volume: 3, P: 1-5
Two distinct populations of Bovine IL-17⁺ T-cells can be induced and WC1⁺IL-17⁺γδ T-cells are effective killers of protozoan parasites

R. K. Peckham
R. Brill
R. J. Flynn
ResearchOpen Access25 Jun 2014
Scientific Reports

Volume: 4, P: 1-5
Observation of the effect of gravity on the motion of antimatter

Magnetically confined neutral antihydrogen atoms released in a gravity field were found to fall towards Earth like ordinary matter, in accordance with Einstein’s general theory of relativity.

E. K. Anderson
C. J. Baker
J. S. Wurtele
ResearchOpen Access27 Sept 2023
Nature

Volume: 621, P: 716-722
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

Epilepsies are common brain disorders and are classified based on clinical phenotyping, imaging and genetics. Here, the authors perform genome-wide association studies for 3 broad and 7 subtypes of epilepsy and identify 16 loci - 11 novel - that are further annotated by eQTL and partitioned heritability analyses.

Bassel Abou-Khalil
Pauls Auce
Fritz Zimprich
ResearchOpen Access10 Dec 2018
Nature Communications

Volume: 9, P: 1-15
Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools

Shawn Minnig
Robert M. Bragg
Jeffrey B. Carroll
ResearchOpen Access02 Feb 2018
Scientific Reports

Volume: 8, P: 1-8
Role of Endogenous Morphine in the Attenuation of Opiate Withdrawal Syndrome by N-acetylmuramyl-L-alanine-D-isoglutamine (MDP)

Inam D Munjal
Dennis Schmidt
Sydney Spector
Research01 Jul 1996
Neuropsychopharmacology

Volume: 15, P: 99-103
The development and structure of the mesentery

Byrnes et al. reconstruct the developing mesentery from digitized embryonic datasets and human and animal cadavers using 3D digital and printed models. They confirm the mesentery remains a continuous organ in and on which all abdominal digestive organs develop and that at the foundation level, the abdomen comprises a mesenteric and non-mesenteric domain.

Kevin G. Byrnes
Dara Walsh
J. Calvin Coffey
ResearchOpen Access18 Aug 2021
Communications Biology

Volume: 4, P: 1-10
Changes in expression of transforming growth factor beta mRNA isoforms in patients undergoing tamoxifen therapy

J MacCallum
JC Keen
WR Miller
Research01 Aug 1996
British Journal of Cancer

Volume: 74, P: 474-478
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Copy number variants (CNVs) account for a major proportion of human genetic diversity and may contribute to genetic susceptibility to disease. Here, a large, genome-wide study of association between common CNVs and eight common human diseases is presented. The study provides a wealth of technical insights that will inform future study design and analysis. The results also indicate that common CNVs that can be 'typed' on existing platforms are unlikely to contribute much to the genetic basis of common diseases.

Nick Craddock
Matthew E. Hurles
Peter Donnelly
Research01 Apr 2010
Nature

Volume: 464, P: 713-720
Prognostic value of nuclear morphometry in patients with TNM stage T1 ovarian clear cell adenocarcinoma

C Q Liu
H Sasaki
T Tanaka
ResearchOpen Access12 Mar 1999
British Journal of Cancer

Volume: 79, P: 1736-1741
Hedgehog signalling in prostate regeneration, neoplasia and metastasis

Sunil S. Karhadkar
G. Steven Bova
Philip A. Beachy
Research12 Sept 2004
Nature

Volume: 431, P: 707-712
Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes

Memory B cells need to be reactivated to produce high affinity antibody responses on subsequent antigen encounters. Here the authors show that memory B cells localise to lymph node subcapsular proliferative foci (SPF), which have distinct properties from the germinal centre, for rapid expansion and the induction of B memory responses.

Imogen Moran
Akira Nguyen
Tri Giang Phan
ResearchOpen Access22 Aug 2018
Nature Communications

Volume: 9, P: 1-14
The effect of artificial selection on phenotypic plasticity in maize

Breeding has increased crop productivity, but whether it has also changed phenotypic plasticity is unclear. Here, the authors find maize genomic regions selected for high productivity show reduced contribution to genotype by environment variation and provide evidence for regulatory control of phenotypic stability.

Joseph L. Gage
Diego Jarquin
Natalia de Leon
ResearchOpen Access07 Nov 2017
Nature Communications

Volume: 8, P: 1-11
Protective efficacy of a Zika purified inactivated virus vaccine candidate during pregnancy in marmosets

In-Jeong Kim
Olga Gonzalez
Jean L. Patterson
ResearchOpen Access17 Feb 2024
npj Vaccines

Volume: 9, P: 1-9
Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy

V Roulstone
K Twigger
K J Harrington
Research16 Aug 2012
Gene Therapy

Volume: 20, P: 521-528
Publisher Correction: Measuring the ionisation fraction in a jet from a massive protostar

R. Fedriani
A. Caratti o Garatti
M. Hoare
Amendments and CorrectionsOpen Access03 Sept 2019
Nature Communications

Volume: 10, P: 1
Synaptic processes and immune-related pathways implicated in Tourette syndrome

Fotis Tsetsos
Dongmei Yu
Samuel Zinner
ResearchOpen Access18 Jan 2021
Translational Psychiatry

Volume: 11, P: 1-12
Aptamers as therapeutics

Aptamers are oligonucleotide sequences that are capable of recognizing target proteins with an affinity and specificity rivalling that of antibodies. In this article, Keefe and colleagues discuss the development, properties and therapeutic potential of aptamers, highlighting those currently in the clinic.

Anthony D. Keefe
Supriya Pai
Andrew Ellington
Reviews01 Jul 2010
Nature Reviews Drug Discovery

Volume: 9, P: 537-550
Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohort

Tanya Simuni
Kalpana Merchant
Johannes Tauscher
ResearchOpen Access22 Oct 2022
npj Parkinson's Disease

Volume: 8, P: 1-10
Exome sequencing identifies NBEAL2 as the causative gene for gray platelet syndrome

Cornelis Albers and colleagues identify NBEAL2 as the causative gene for gray platelet syndrome (GPS). Knockdown of this gene in zebrafish leads to spontaneous bleeding and defects in thrombocyte formation.

Cornelis A Albers
Ana Cvejic
Willem H Ouwehand
Research17 Jul 2011
Nature Genetics

Volume: 43, P: 735-737
The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status

M Kim
C T Williamson
R N Johnston
Research17 May 2010
Oncogene

Volume: 29, P: 3990-3996
Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions

A dynamic view of nuclear function is emerging, in which genomic regions undergo repositioning relative to each other and to nuclear subcompartments. Increasing evidence points to an important contribution of these movements in the regulation of gene expression.

Christian Lanctôt
Thierry Cheutin
Thomas Cremer
Reviews01 Feb 2007
Nature Reviews Genetics

Volume: 8, P: 104-115
GH PREINCUBATION FAILS TO INDUCE RESISTANCE TO THE MITOGCNIC ACTION OF INSULIN IN A PYGMY T-CELL LINE

M E Geffner
N Bersch
D W Golde
Research01 May 1993
Pediatric Research

Volume: 33, P: S67
RESPONSE TO TWICE-DAILY DOSING OF MET-GH IN NAIVE GH DEFICIENT PATIENTS

R Levy
D Norman
Colleen Miller
Research01 May 1993
Pediatric Research

Volume: 33, P: S67
INSULIN-LIKE GROWTH FACTORS (IGFs) STIMULATE VLA-4 INTEGRIN GENE EXPRESSION IN DIFFERENTIATING MOUSE SKELETAL MUSCLE CELLS

S M Rosenthal
D Hsiao
Research01 May 1993
Pediatric Research

Volume: 33, P: S67
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

Using large-scale exome sequencing, this study identifies a second (after VHL) frequently mutated gene in clear cell renal cell carcinomas, the most frequent type of kidney cancer. PBRM1, a member of the SWI/SNF complex involved in transcriptional regulation, is mutated in about 40% of cases and shown to function as tumour suppressor gene. PBRM1 was independently found as a putative cancer gene involved in pancreatic cancer in a mouse transposon screen.

Ignacio Varela
Patrick Tarpey
P. Andrew Futreal
Research19 Jan 2011
Nature

Volume: 469, P: 539-542
Aerobic exercise intensity does not affect the anabolic signaling following resistance exercise in endurance athletes

T. W. Jones
L. Eddens
G. Howatson
ResearchOpen Access24 May 2021
Scientific Reports

Volume: 11, P: 1-11
CEP152 is a genome maintenance protein disrupted in Seckel syndrome

Bernd Wollnik and colleagues report mutations in CEP152 cause Seckel syndrome, which is characterized by short stature, severe microcephaly and mental retardation. The work suggests that CEP152 has a function in genome maintenance.

Ersan Kalay
Gökhan Yigit
Bernd Wollnik
Research05 Dec 2010
Nature Genetics

Volume: 43, P: 23-26
A computational model for predicting changes in infection dynamics due to leakage through N95 respirators

Prasanna Hariharan
Neha Sharma
Matthew R. Myers
ResearchOpen Access21 May 2021
Scientific Reports

Volume: 11, P: 1-19
Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms

S A Gujar
D Clements
P W K Lee
ResearchOpen Access26 Nov 2013
British Journal of Cancer

Volume: 110, P: 83-93
Using deep learning to detect digitally encoded DNA trigger for Trojan malware in Bio-Cyber attacks

M. S. Islam
S. Ivanov
W. Sri-saan
ResearchOpen Access10 Jun 2022
Scientific Reports

Volume: 12, P: 1-13
The history of cancer epigenetics

Andrew P. Feinberg
Benjamin Tycko
Reviews01 Feb 2004
Nature Reviews Cancer

Volume: 4, P: 143-153
Dichotic Listening before and after Fluoxetine Treatment for Major Depression: Relations of Laterality to Therapeutic Response

Gerard E Bruder
Michael W Otto
Frederic M Quitkin
Research01 Aug 1996
Neuropsychopharmacology

Volume: 15, P: 171-179
Epidermal growth factor receptor expression by human squamous cell carcinomas of the head and neck, cell lines and xenografts

P Stanton
S Richards
BW Ozanne
Research01 Sept 1994
British Journal of Cancer

Volume: 70, P: 427-433
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss

Trey Ideker and colleagues report a comprehensive genome-wide analysis of head and neck squamous cell carcinoma, reporting that TP53 mutations are frequently accompanied by loss of chromosome 3p. Their data indicate that the combination of these two events has a stronger negative effect on survival rate than either event alone.

Andrew M Gross
Ryan K Orosco
Trey Ideker
Research01 Sept 2014
Nature Genetics

Volume: 46, P: 939-943
Spectral morphometric characterization of breast carcinoma cells

I Barshack
J Kopolovic
C Rothmann
ResearchOpen Access26 Feb 1999
British Journal of Cancer

Volume: 79, P: 1613-1619
Down-regulation of TGF-β 1 production restores immunogenicity in prostate cancer cells

E Matthews
T Yang
C Lee
ResearchOpen Access25 Jul 2000
British Journal of Cancer

Volume: 83, P: 519-525
Divertor shaping with neutral baffling as a solution to the tokamak power exhaust challenge

Power exhaust is one of the biggest challenges stopping fusion energy. This article shows experimental evidence for strategically shaping the power exhaust region as a solution to this challenge, utilising physics understanding to strike a balance between engineering complexity and power exhaust benefits, consistent with reduced models and simulations.

Kevin Verhaegh
James Harrison
V. Zamkovska
ResearchOpen Access23 May 2025
Communications Physics

Volume: 8, P: 1-15
Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein

Urszula L McClurg
Arash Nabbi
Olivier Binda
ResearchOpen Access30 Jan 2018
British Journal of Cancer

Volume: 118, P: 713-726

Search

Filter By:

Search

Quick links