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Showing 51–100 of 357 results

Advanced filters: Author: D. Raynaud Clear advanced filters

Climatic Implications of Total Gas Content in Ice at Camp Century

D. RAYNAUD
C. LORIUS
Research01 Jun 1973
Nature

Volume: 243, P: 283-284
Two-phase change in CO₂, Antarctic temperature and global climate during Termination II

Glacial Termination II was marked by a rise in atmospheric CO₂ concentrations and global temperature. An analysis of air bubbles from an Antarctic ice core suggests that during the first phase of deglaciation, Antarctic temperature and atmospheric CO₂ concentrations increased together, whereas CO₂ lagged behind temperature rise during the second phase.

A. Landais
G. Dreyfus
G. Teste
Research20 Oct 2013
Nature Geoscience

Volume: 6, P: 1062-1065
Antarctic ice volume and contribution to sea-level fall at 20,000 yr BP from raised beaches

E. A. Colhoun
M. C. G. Mabin
R. M. Kirk
Research23 Jul 1992
Nature

Volume: 358, P: 316-319
Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations

Vein of Galen malformations (VOGMs) are severe congenital brain arteriovenous malformations. Here the authors work to elucidate the pathogenesis of VOGMs by performing an integrated analysis of 310 VOGM proband family exomes and 336,326 human cerebrovasculature single-cell transcriptomes to identify mutations of key signaling regulators.

Shujuan Zhao
Kedous Y. Mekbib
Kristopher T. Kahle
ResearchOpen Access17 Nov 2023
Nature Communications

Volume: 14, P: 1-23
Vostok ice core: climatic response to CO₂ and orbital forcing changes over the last climatic cycle

G. Genthon
J. M. Barnola
V. M. Kotlyakov
Research01 Oct 1987
Nature

Volume: 329, P: 414-418
Largest known microbialites discovered in Lake Van, Turkey

S. Kempe
J. Kazmierczak
A. Lipp
Research14 Feb 1991
Nature

Volume: 349, P: 605-608
Moving towards a molecular taxonomy of autoimmune rheumatic diseases

The heterogeneity of autoimmune rheumatic diseases, and their shared clinical and molecular features, makes classifying and diagnosing these diseases difficult and highlights the need for a new taxonomy. Reclassifying these diseases according to the underlying molecular mechanisms might lead to novel insights into disease mechanisms and enable better patient stratification.

Guillermo Barturen
Lorenzo Beretta
Marta E. Alarcón-Riquelme
Reviews24 Jan 2018
Nature Reviews Rheumatology

Volume: 14, P: 75-93
International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: an International Myositis Assessment and Clinical Studies Group (IMACS) initiative

In this Evidence-Based Guideline article, an international, multidisciplinary group of experts presents evidence-based consensus recommendations on screening for cancer in patients with adult-onset idiopathic inflammatory myopathy, addressing cancer risk stratification, screening modalities and screening frequency.

Alexander G. S. Oldroyd
Jeffrey P. Callen
Rohit Aggarwal
Reviews09 Nov 2023
Nature Reviews Rheumatology

Volume: 19, P: 805-817
Augmentation of Cytotoxic Drug Action by Antibodies Directed at Cell Surface

ROBERT D. RUBENS
RENATO DULBECCO
Research01 Mar 1974
Nature

Volume: 248, P: 81-82
A receptor mediating sexual differentiation?

JACKIE BARLEY
M. GINSBURG
P. J. THOMAS
Research15 Nov 1974
Nature

Volume: 252, P: 259-260
Results from a living systematic review of the prevalence of mood and anxiety disorders and factors associated with symptoms in systemic sclerosis

Elsa-Lynn Nassar
Dalal A. Abdulkareem
Brett D. Thombs
ResearchOpen Access30 Mar 2023
Scientific Reports

Volume: 13, P: 1-10
Treatment of digital ulcers in systemic sclerosis

Digital ulcers in patients with systemic sclerosis (SSc) can cause considerable disability; however, clinical trials addressing the treatment and prevention of digital ulcers in SSc are rare. A study has evaluated the potential benefit of the endothelin receptor antagonist bosentan in the treatment of SSc-related digital ulcers.

Sevdalina Lambova
Ulf Müller-Ladner
News & Views30 Nov 2010
Nature Reviews Rheumatology

Volume: 7, P: 5-6
Mechanisms of Disease: the role of immune cells in the pathogenesis of systemic sclerosis

Research into the pathogenesis of systemic scleroderma has highlighted the important role for activated immune cells in this process. These cells and the soluble mediators they produce, therefore, represent logical targets for therapeutic intervention in this disease, as discussed in this Review.

Lazaros I Sakkas
Ian C Chikanza
Chris D Platsoucas
Reviews01 Dec 2006
Nature Clinical Practice Rheumatology

Volume: 2, P: 679-685
Impact of HLA evolutionary divergence and donor-recipient molecular mismatches on antibody-mediated rejection of kidney allografts

Kidney transplants are at risk of graft failure due to immune system rejection. Here, the authors assess a broad range of clinical and immunological baseline variables in a large, unselected kidney transplant cohort, providing further insights into factors associated with antibody-mediated rejection

Zeynep Demir
Marc Raynaud
Alexandre Loupy
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-11
Holograms in algal suspensions

K. M. Brown
K. Lamb
R. Illingworth
Research26 May 1994
Nature

Volume: 369, P: 282-283
Isotopic composition of atmospheric O₂ in ice linked with deglaciation and global primary productivity

M. Bender
L. D. Labeyrie
C. Lorius
Research28 Nov 1985
Nature

Volume: 318, P: 349-352
Adjuvant activity in delayed hypersensitivity of the peptidic part of bacterial peptidoglycans

J. FLECK
M. MOCK
R. MINCK
Research09 Aug 1974
Nature

Volume: 250, P: 517-518
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis

Systemic sclerosis (SSc) is an autoimmune disease causing skin fibrosis and organ inflammation. Here the authors generate and analyze SSc skin single cell RNA sequencing data to propose contributions from both myofibroblasts and endothelial-to-mesenchymal -transitioning cells (EndoMT) to skin fibrosis, and to implicate the involvement of Hippo signaling pathways.

Feiyang Ma
Pei-Suen Tsou
Johann E. Gudjonsson
ResearchOpen Access03 Jan 2024
Nature Communications

Volume: 15, P: 1-17
Carcinogenic Activity of Apocholic Acid

A. LACASSAGNE
N. P. BUU-HOÏ
F. ZAJDELA
Research10 Jun 1961
Nature

Volume: 190, P: 1007-1008
The role of platelets in immune-mediated inflammatory diseases

In addition to their well-established role in haemostasis, platelets also have an active role in the immune response. Here the authors summarize the evidence linking platelet activation to immune dysregulation and organ damage in immune-mediated inflammatory diseases, and discuss the therapeutic potential of targeting platelets.

Marc Scherlinger
Christophe Richez
Patrick Blanco
Reviews27 Jan 2023
Nature Reviews Immunology

Volume: 23, P: 495-510
Cell-free DNA for the detection of kidney allograft rejection

A prospective observational study including 2,882 kidney allograft recipients from 14 transplantation centers in Europe and the United States shows that cell-free DNA can be used to detect kidney allograft rejection.

Olivier Aubert
Cindy Ursule-Dufait
Alexandre Loupy
ResearchOpen Access02 Jun 2024
Nature Medicine

Volume: 30, P: 2320-2327
Melting history of Antarctica during the past 60,000 years

L. D. Labeyrie
J. J. Pichon
J. C. Duplessy
Research21 Aug 1986
Nature

Volume: 322, P: 701-706
Variations in atmospheric methane concentration during the Holocene epoch

T. Blunier
J. Chappellaz
D. Raynaud
Research02 Mar 1995
Nature

Volume: 374, P: 46-49
Glacial-to-interglacial variations in the carbon isotopic composition of atmospheric CO₂

Bruno D. Marino
Michael B. McElroy
W. Geoffrey Spaulding
Research11 Jun 1992
Nature

Volume: 357, P: 461-466
A deep hydrological front between intermediate and deep-wafpr , masses in the glacial Indian Ocean

Nejib Kallel
Laurent D. Labeyrie
Jean-Claude Duplessy
Research16 Jun 1988
Nature

Volume: 333, P: 651-655
Differentiating between UCTD and early-stage SLE: from definitions to clinical approach

Differentiating between the early stages of systemic lupus erythematosus (SLE) and undifferentiated connective tissue disease (UCTD) can be challenging. In this Review, the authors summarize current knowledge on UCTD and early-stage SLE and discuss clinical approaches to diagnosing these conditions.

Savino Sciascia
Dario Roccatello
Marta Mosca
Reviews11 Nov 2021
Nature Reviews Rheumatology

Volume: 18, P: 9-21
High-resolution carbon dioxide concentration record 650,000–800,000 years before present

Dieter Lüthi
Martine Le Floch
Thomas F. Stocker
Research15 May 2008
Nature

Volume: 453, P: 379-382
Increased particle flux to the deep ocean related to monsoons

R. R. Nair
V. Ittekkot
S. Honjo
Research27 Apr 1989
Nature

Volume: 338, P: 749-751
Ice cores north and south

Jean Jouzel
News & Views15 Dec 1994
Nature

Volume: 372, P: 612-613
N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis

Edoardo Rosato
Rosario Cianci
Felice Salsano
Research04 Sept 2009
Acta Pharmacologica Sinica

Volume: 30, P: 1283-1288
Steroid hydrocarbons and the thermal history of sediments

A. S. Mackenzie
N. A. Lamb
J. R. Maxwell
Research21 Jan 1982
Nature

Volume: 295, P: 223-226
RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock

Histamine causes vascular leakage by a direct and yet mechanistically poorly defined effect on endothelium. Here, the authors show that histamine elicits endothelial RhoA/Rock signaling and that inhibition of this pathway preserves the vascular barrier, thereby identifying novel pharmacological targets for histamine-mediated diseases.

Constantinos M. Mikelis
May Simaan
J. Silvio Gutkind
Research10 Apr 2015
Nature Communications

Volume: 6, P: 1-11
High-resolution record of Northern Hemisphere climate extending into the last interglacial period

K. K. Andersen
N. Azuma
J. W. C. White
Research09 Sept 2004
Nature

Volume: 431, P: 147-151
Nonsteroidal compounds which bind epididymal androgen-binding protein but not the androgen receptor

Guy G. Rousseau
Jacques I. Quivy
Raymond Devis
Research03 Apr 1980
Nature

Volume: 284, P: 458-459
Contact electrification induced by monolayer modification of a surface and relation to acid–base interactions

R. G. Horn
D. T. Smith
A. Grabbe
Research02 Dec 1993
Nature

Volume: 366, P: 442-443
Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1

J Adélaide
G Monges
D Birnbaum
Research01 Jan 1995
British Journal of Cancer

Volume: 71, P: 64-68
Toxin Treatise

D. E. DOLBY
Books & Arts29 Aug 1970
Nature

Volume: 227, P: 978-979
Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature

Yanick Crow and colleagues show that mutations in ACP5, which encodes tartrate-resistant acid phosphatase, cause spondyloenchondrodysplasia, a bone dysplasia with autoimmunity. The affected individuals had elevated serum interferon alpha activity.

Tracy A Briggs
Gillian I Rice
Yanick J Crow
Research09 Jan 2011
Nature Genetics

Volume: 43, P: 127-131
Long term outcomes of the French ASTIS systemic sclerosis cohort using the global rank composite score

Nassim Ait Abdallah
Mianbo Wang
Dominique Farge
Research09 Jun 2021
Bone Marrow Transplantation

Volume: 56, P: 2259-2267
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation

Here the authors find that erythroblasts of myelodysplastic syndromes with SF3B1 mutation leading to inefficient erythropoiesis show DNA replication stress with accelerated forks and reduced R-loops. Restoring R-loops by a histone deacetylase inhibitor rescues erythroid differentiation.

David Rombaut
Carine Lefèvre
Michaela Fontenay
ResearchOpen Access08 Apr 2024
Nature Communications

Volume: 15, P: 1-20
The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions

Michael D. Blower
Gary H. Karpen
Research12 Jul 2001
Nature Cell Biology

Volume: 3, P: 730-739
Androgen-induced Sexual Differentiation of the Brain is Blocked by Inhibitors of DNA and RNA Synthesis

D. F. SALAMAN
SONIA BIRKETT
Research11 Jan 1974
Nature

Volume: 247, P: 109-112
Inflammatory profile of induced sputum composition in systemic sclerosis and comparison with healthy volunteers

P. Jacquerie
M. Henket
J. Guiot
ResearchOpen Access21 May 2021
Scientific Reports

Volume: 11, P: 1-10
Serum metabolites as biomarkers in systemic sclerosis-associated interstitial lung disease

C. Meier
K. Freiburghaus
B. Maurer
ResearchOpen Access14 Dec 2020
Scientific Reports

Volume: 10, P: 1-14
Role of transition-metal catalysis in the formation of natural gas

Frank D. Mango
J. W. Hightower
Alan T. James
Research07 Apr 1994
Nature

Volume: 368, P: 536-538
Barium content of benthic foraminifera controlled by bottom-water composition

D. Lea
E. Boyle
Research27 Apr 1989
Nature

Volume: 338, P: 751-753
Summer dryness in northern mid-latitudes due to increased CO₂

J. F. B. Mitchell
D. A. Warrilow
Research19 Nov 1987
Nature

Volume: 330, P: 238-240
Calcium-dependent stimulation of platelet aggregation by PGE₂

D. E. MACINTYRE
J. L. GORDON
Research27 Nov 1975
Nature

Volume: 258, P: 337-339
Seasonal variations in endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerine-induced vasodilation

Tatsuya Maruhashi
Masato Kajikawa
Yukihito Higashi
Research15 Nov 2023
Hypertension Research

Volume: 47, P: 910-920
Temperature measurements during initiation and growth of a black smoker chimney

M. K. Tivey
L. O. Olson
R. D. Light
Research05 Jul 1990
Nature

Volume: 346, P: 51-54

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