Neurocognitive impairment is a frequent manifestation of systemic lupus erythematosus in pediatric patients; however, the evidence base for the epidemiology, pathogenesis, diagnosis and treatment of this phenomenon is limited. The authors of this Review article discuss the available data and highlight avenues for future research in this clinically important field.
- Deborah M Levy
- Stacy P Ardoin
- Laura E Schanberg