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Showing 1–3 of 3 results
Advanced filters: Author: Da-Long Cao Clear advanced filters
  • Many clear cell renal cell carcinoma (ccRCC) patients do not respond or develop resistance to tyrosine kinase inhibitors, such as Sunitinib. Here, the authors perform a proteogenomics analysis of Chinese ccRCC patients treated with Sunitinib and develop a multi-omics classifier to distinguish responders from non-responders.

    • Hailiang Zhang
    • Lin Bai
    • Chen Ding
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-21
  • Clear cell renal cell carcinoma is an aggressive form of renal cancer, with differences in genomic mutations reported between Western and Eastern populations. In this study, the authors have compiled proteogenomic analysis of Chinese ccRCC to reveal genomic alterations and dysregulation of immune and metabolic responses.

    • Yuanyuan Qu
    • Jinwen Feng
    • Chen Ding
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-21
  • The molecular landscape of microphthalmia transcription factor family translocation renal cell carcinoma tumours remain to be characterised. Here, the authors perform proteogenomic analysis and reveal dysregulation of DNA repair, mTOR signalling and metabolic processes.

    • Yuanyuan Qu
    • Xiaohui Wu
    • Chen Ding
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18