Cholinergic signalling modulates learning and memory; however, its influence on learning-induced synaptic plasticity is less clear. Mitsushima et al.show that acetylcholine simultaneously strengthens both excitatory and inhibitory synapses onto CA1 pyramidal neurons following an inhibitory avoidance task.
- Dai Mitsushima
- Akane Sano
- Takuya Takahashi