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Controlling magnetic domain wall motion in nanowires requires a thorough knowledge of the depinning mechanisms. Here, the authors show that current-induced intrinsic depinning has a different energy barrier than magnetic field-induced extrinsic depinning, and succeed in quantifying the respective barriers.

The direction of strain in a material can be detected using flexible giant magnetoresistive devices that consist of a strain-sensitive free layer and a strain-insensitive pinned layer.

In vitro studies in human cell lines and in vivo studies in a hamster model show that the SARS-CoV-2 Omicron variant is less pathogenic than both the Delta variant and an ancestral strain of SARS-CoV-2.

BRD9 is a core non-canonical BAF component. Here the authors show that BRD9 plays a pivotal role in regulating the disease-related cell fate of hematopoietic stem cells. Its loss promotes myeloid skewing while impairing B cell development by altering CTCF-mediated chromatin states.

EGFR mutations in lung adenocarcinoma are more frequent in East Asians compared to other populations. Here, the authors carry out a genome-wide association study in EGFRmutant cancers and identify loci that are associated with risk of developing this molecular subtype of cancer.

The transition from a ferromagnetic to a paramagnetic state is observed directly as the density of carriers that mediate spin–spin coupling is varied. The measurement was performed on thin films of GaMnAs and was made possible by superconducting quantum interference devices (SQUIDS).

The spike protein of the Omicron variant of SARS-CoV-2 has a higher affinity for ACE2 than Delta, and a marked change in its antigenicity increases Omicron’s evasion of therapeutic and vaccine-elicited neutralizing antibodies.

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Dzyaloshinskii–Moriya interaction (DMI) is one of the key factors to control the chiral spin textures in spintronic applications. Here the authors demonstrate the correlation of the DMI with the anisotropy of the orbital magnetic moment and magnetic dipole moment in Pt/Co/MgO ultrathin trilayers.

Adult neural stem cells are derived from an embryonic population of slowcycling progenitor cells, though how reduced cycling speed leads to establishment of the adult population has remained elusive. Here they show that non-oscillatory Notch-Hey signaling induced by slow-cycling contributes to long term maintenance of neural stem cells.

Plant colonization of land is an important evolutionary event. Here, the authors sequence the genome of a filamentous terrestrial alga and, through a comparative analysis with related algae and land plant species, provide insight into how aquatic algae adapted to terrestrial environments.

The intercalation of metal ions in layered structures has a wide variety of applications, from energy storage to environmental remediation. Here the authors report that layered telluride structures can selectively bind transition metals and this intercalation can occur in solid state at mild conditions.

The electric field in a Schottky barrier can be used to control spin–orbit magnetic fields.

The authors demonstrate magnetoresistance of 80% from a two-dimensional electron gas proximity coupled to a ferromagnetic layer. This extends spintronics functionality to semiconductor devices.

Seishi Ogawa and colleagues report an integrated genomics analysis of more than 100 clear-cell renal carcinoma samples. They analyze whole genomes or exomes, RNA sequences and DNA methylation in ∼100 paired specimens and perform SNP array-based copy number analysis for 240 specimens. They identify new recurrently mutated pathways and new associations between DNA methylation, mutations, gene expression and copy number profiles.

XBB.1.5 of SARS-CoV-2 is a descendant of XBB.1 and has mutations in spike and ORF8, making it more infectious to humans. Here, the authors examined in detail the differences in virological properties of the two variants.

Ion-conductive behavior of a novel polymer electrolyte without oxyethylene units, poly(ethylene carbonate) (PEC)-Li salt system, was reported. Salt-concentration dependence revealed that the LiCF₃SO₃ and LiClO₄ electrolytes exhibit typical polyether-like conduction behavior. However, the LiBETI, LiBF₄ and LiTFSI electrolytes were much different, and the conductivity increased and T_g decreased with increasing salt concentration. This behavior of salt-rich PEC electrolytes relates to the ‘polymer-in-salt’ system. Li⁺ transference number of PEC-LiBF₄ (44.4 wt%) electrolyte was measured, and the value was estimated to be ∼0.5 at 100 ^oC.

The virological and pathological features of Omicron subvariants are compared in in vitro cellular and airway-on-a-chip and in vivo hamster models.

In this study, Higashiyama and colleagues examine pollen tube guidance in Torenia fournieri and identify the secreted guidance factors. These are cysteine-rich polypeptides belonging to the subgroup of defensin-like proteins (designated as LUREs), which are predominantly expressed in synergid cells and are required for pollen tube guidance.

The authors developed a CUBIC tissue clearing and expansion method to generate an editable, point-based single-cell-resolution brain atlas. This atlas, termed CUBIC-Atlas, can be used for unbiased systems-level cellular analysis in whole mouse brain.

Data-driven machine learning algorithm, Syntactic Motion Parser, automatically decomposes primate’s natural motion dynamics into its inherent component.

Gen Sobue, Masao Nagasaki and colleagues report a genome-wide association study for amyotrophic lateral sclerosis (ALS) in a large, multi-ethnic cohort comprising Japanese, Chinese, and European ancestry populations. They find a significant association to variants within the ACSL5 gene and identify novel associations with 4 additional genes using a gene-based approach.

Alkylated dinaphtho[2,3-b:2',3'-d]furan (DNF–V) derivatives are systematically investigated in view of the impact of the substitution position as well as length of alkyl side chains. For both alkylated DNF–VV and DNF–VW derivatives, the solubilities as well as phase-transition temperatures increase as the shorter alkyl chains are attached. Especially, alkylated DNF–VV simultaneously gain the high solubility over 1 wt% and highly stabilized crystal phase up to 199 °C. Furthermore, DNF–V derivatives exhibit deep-blue emission in solid state with the quantum efficiency ranging from 17 to 51%.