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Treating comorbid post-traumatic stress and depression in perinatal populations: findings from a pragmatic randomized controlled trial

Singla et al. report the secondary analysis of the Scaling Up Maternal Mental healthcare by Increasing access to Treatment (SUMMIT) trial.

Daisy R. Singla
Tara S. Berenbaum
Vikram Patel
Research08 Oct 2025
Nature Mental Health

Volume: 3, P: 1342-1351
Evidence-based psychotherapies for perinatal mood and anxiety disorders and their underlying mechanisms

Perinatal mood and anxiety disorders affect one in five women during pregnancy and up to one year postpartum and are a strong predictor of perinatal suicidality. In this Review, Singla et al. provide an overview of evidence-based psychotherapies for perinatal depression, anxiety, post-traumatic stress and suicidality and describe their underlying mechanisms.

Daisy R. Singla
Andrea S. Lawson
Crystal E. Schiller
Reviews04 Nov 2025
Nature Reviews Psychology

Volume: 4, P: 761-776
Task-sharing and telemedicine delivery of psychotherapy to treat perinatal depression: a pragmatic, noninferiority randomized trial

A multinational randomized trial shows that task-sharing via nonspecialist providers and the use of telemedicine platforms, delivery models that can overcome barriers to scalability and access, are noninferior to specialists and in-person models for treating perinatal depression.

Daisy R. Singla
Richard K. Silver
Samantha Meltzer-Brody
ResearchOpen Access03 Mar 2025
Nature Medicine

Volume: 31, P: 1214-1224
Expanding the reach and scalability of perinatal mental health interventions

A new study shows the benefits of treating anxiety to prevent postnatal depression — and highlights the need for more pragmatic research to simplify treatment packages, address other comorbid symptoms, and deliver effective perinatal mental health care at scale.

Daisy R. Singla
News & Views26 Feb 2024
Nature Medicine

Volume: 30, P: 638-639
Advancing telemedicine and task-sharing to improve access to psychotherapy for perinatal populations

Andrejek et al. evaluate the barriers and facilitators of leveraging telemedicine and task-sharing to improve access to psychotherapy for perinatal patients with symptoms of depression and anxiety in the SUMMIT trial. The qualitative implementation assessment demonstrates that both solutions are feasible, patient-centered approaches.

Nicole Andrejek
Zoë Lea
Daisy R. Singla
ResearchOpen Access30 Sept 2025
Communications Medicine

Volume: 5, P: 1-10

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Treating comorbid post-traumatic stress and depression in perinatal populations: findings from a pragmatic randomized controlled trial

Evidence-based psychotherapies for perinatal mood and anxiety disorders and their underlying mechanisms

Task-sharing and telemedicine delivery of psychotherapy to treat perinatal depression: a pragmatic, noninferiority randomized trial

Expanding the reach and scalability of perinatal mental health interventions

Advancing telemedicine and task-sharing to improve access to psychotherapy for perinatal populations

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