In this Review, the authors describe the key epigenetic events that are associated with the differentiation and function of cells of the myeloid lineage, with a particular emphasis on monocytes and macrophages. They detail the epigenetic enzymes that control these events and discuss emerging data that show the importance of epigenetic regulation for 'memory-like' behaviour in innate immune cells.
- Damiana Álvarez-Errico
- Roser Vento-Tormo
- Esteban Ballestar