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Showing 1–9 of 9 results

Advanced filters: Author: Damu Wu Clear advanced filters

Author Correction: Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition

Chengying Ma
Damu Wu
Ning Gao
Amendments and CorrectionsOpen Access27 Jan 2023
Nature Communications

Volume: 14, P: 1
Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition

Drg1 is a cytoplasmic AAA + ATPase responsible for releasing Rlp24 during ribosome assembly. Here, the authors show that Drg1 structurally and functionally shares many regulatory features with that of Cdc48/p97, suggesting a unfoldase role for Drg1.

Chengying Ma
Damu Wu
Ning Gao
ResearchOpen Access09 Nov 2022
Nature Communications

Volume: 13, P: 1-16
Cryo-EM structure of the AAA+ SPATA5 complex and its role in human cytoplasmic pre-60S maturation

Eukaryotic ribosome assembly involves multiple AAA+ ATPase hexamer mediated maturation steps. Here, authors report the structural analysis of the human SPATA5/SPATA5L1/CINP/C1ORF109 ATPase complex, revealing its role in cytoplasmic pre-60S maturation.

Yuhao Dai
Damu Wu
Ning Gao
ResearchOpen Access23 Apr 2025
Nature Communications

Volume: 16, P: 1-14
DddA homolog search and engineering expand sequence compatibility of mitochondrial base editing

There is a need to improve and expand mitochondrial base editing tools. Here the authors identify a DddA homolog from Simiaoa sunii (Ddd_Ss) which can efficiently deaminate cytosine in dsDNA; they develop cytosine base editors and introduce mutations at multiple mitochondrial DNA loci.

Li Mi
Ming Shi
Yangming Wang
ResearchOpen Access16 Feb 2023
Nature Communications

Volume: 14, P: 1-9
Peroxiredoxin 1 promotes intestinal inflammation by activating the NLRP3 inflammasome in macrophages through lysosomal disruption in Crohn’s disease

Shenglan Li
Qiuping Xia
Zhangzhe Peng
ResearchOpen Access26 Jul 2025
Cell Death & Disease

Volume: 16, P: 1-16
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival

Melatonin induces Parkin 1 dependent mitophagy in human umbilical vein endothelial cells through the AMPK/TFEB pathway, alleviating oxidative stress and apoptosis, which also enables skin flap survival in vivo.

Zhengtai Chen
Hongqiang Wu
Weiyang Gao
ResearchOpen Access22 Jun 2022
Communications Biology

Volume: 5, P: 1-14
ATM activity contributes to the tumor-suppressing functions of p14^ARF

Yanxia Li
Dongcheng Wu
Damu Tang
Research19 Jul 2004
Oncogene

Volume: 23, P: 7355-7365
Frequent allelic deletion at the FHIT locus associated with p53 overexpression in squamous cell carcinoma subtype of Taiwanese non-small-cell lung cancers

Y-C Lee
C-T Wu
Y-L Chang
ResearchOpen Access04 May 2004
British Journal of Cancer

Volume: 90, P: 2378-2383
Roles of Fhit and p53 in Taiwanese surgically treated non-small-cell lung cancers

Y-L Chang
C-T Wu
Y-C Lee
ResearchOpen Access15 Jul 2003
British Journal of Cancer

Volume: 89, P: 320-326