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Showing 1–2 of 2 results
Advanced filters: Author: Dana Motabar Clear advanced filters

  • A method called mediated electrochemical probing (MEP) was developed, which enables the rapid conversion of information about structural perturbations of proteins into convenient, readily accessible electronic data. MEP was used to detect structural variants of a monoclonal antibody by discerning patterns associated with the antibody’s mediator-accessible redox activity.

    • Dana Motabar
    • Eunkyoung Kim
    • William E. Bentley
    Research
    Nature Chemical Biology
    Volume: 21, P: 291-299

  • In this work the authors investigate the structure-sequence dependance. The ability to design and characterize proteins at interfaces between three common folds suggests that fold switching is an intrinsic feature of protein folding language and likely important in the evolution of protein structure and function.

    • Biao Ruan
    • Yanan He
    • Philip N. Bryan
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14