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Showing 1–2 of 2 results
Advanced filters: Author: Daniel Ben-Isvy Clear advanced filters

  • This study in the Finnish population reveals genetic reduction of the complement factor CFHR5 as enhancing retinal health and reducing the risk for age-related macular degeneration (AMD), suggesting new strategies for AMD prevention and treatment.

    • Mary Pat Reeve
    • Stephanie Loomis
    • Heiko Runz
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • MuSiCal is a mutational signature analysis tool combining minimum-volume nonnegative matrix factorization with other algorithmic innovations. Applied to PCAWG data, MuSiCal gives more accurate results, including resolving ambiguous flat signatures.

    • Hu Jin
    • Doga C. Gulhan
    • Peter J. Park
    ResearchOpen Access
    Nature Genetics
    Volume: 56, P: 541-552