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Showing 1–4 of 4 results
Advanced filters: Author: Daniel J. Weix Clear advanced filters

  • A new method for catalysing the cross-coupling of two different aryl electrophiles is described; the principle of this method, which involves cooperation between two metal catalysts that are selective towards different substrates, should be generally useful in catalysis.

    • Laura K. G. Ackerman
    • Matthew M. Lovell
    • Daniel J. Weix
    Research
    Nature
    Volume: 524, P: 454-457

  • Pharmaceutical compound libraries are an essential part of drug discovery and the screening of libraries for new drug leads is routine. It has now been shown that these heterocycle-rich, diverse libraries can also be used for ligand discovery. The discovery and application of several new ligands to nickel-catalysed cross-electrophile coupling is demonstrated.

    • Eric C. Hansen
    • Dylan J. Pedro
    • Daniel J. Weix
    Research
    Nature Chemistry
    Volume: 8, P: 1126-1130

  • A quinone-mediated hydrogen anode design shows that hydrogen can be used as the electron source in non-aqueous reductive electrosynthesis, for a more sustainable way to make molecules at larger scale.

    • Jack Twilton
    • Mathew R. Johnson
    • Shannon S. Stahl
    Research
    Nature
    Volume: 623, P: 71-76

  • Carbon–carbon single bonds are generally among the least reactive chemical bonds. While olefin metathesis reactions are well established, direct metathesis of C–C single bonds is rare. Now, a C–C single bond metathesis reaction has been developed, forming cross-biaryl products from unstrained homo-biaryl compounds.

    • Michael M. Gilbert
    • Daniel J. Weix
    News & Views
    Nature Chemistry
    Volume: 13, P: 818-820