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Showing 1–6 of 6 results

Advanced filters: Author: Daniel Ladant Clear advanced filters

Interplay between T3SS effectors, ExoY activation, and cGMP signaling in Pseudomonas aeruginosa infection

The Type 3 Secretion System (T3SS) of Pseudomonas aeruginosa injects effectors into host cells to promote infection. Here, the authors reveal a new regulatory role for the T3SS effector ExoY in modulating ExoT-induced cytotoxicity via cGMP signalling.

Vincent Deruelle
Gabrielle Dupuis
Undine Mechold
ResearchOpen Access02 Dec 2025
Nature Communications

Volume: 17, P: 1-21
Extinction intensity during Ordovician and Cenozoic glaciations explained by cooling and palaeogeography

High extinction intensity during Late Ordovician but not Cenozoic transitions to glacial conditions can be attributed to both temperature and palaeogeography, according to analysis combining climate models and simulations of virtual species.

Erin E. Saupe
Huijie Qiao
Seth Finnegan
Research16 Dec 2019
Nature Geoscience

Volume: 13, P: 65-70
Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

The ExoY toxin is injected by Pseudomonas aeruginosainto host cells, where it is activated by an unknown host factor. Here the authors identify such factor as filamentous actin.

Alexander Belyy
Dorothée Raoux-Barbot
Undine Mechold
ResearchOpen Access05 Dec 2016
Nature Communications

Volume: 7, P: 1-14
Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis

Sara E. Cannella
Véronique Yvette Ntsogo Enguéné
Alexandre Chenal
ResearchOpen Access10 Feb 2017
Scientific Reports

Volume: 7, P: 1-17
DeepMIP-Eocene-p1: multi-model dataset and interactive web application for Eocene climate research

Sebastian Steinig
Ayako Abe-Ouchi
Daniel J. Lunt
ResearchOpen Access05 Sept 2024
Scientific Data

Volume: 11, P: 1-13
Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

Darragh P. O’Brien
Belen Hernandez
Alexandre Chenal
ResearchOpen Access16 Sept 2015
Scientific Reports

Volume: 5, P: 1-11