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Advanced filters: Author: Daniel Lesman Clear advanced filters

Photoselective sequencing: microscopically guided genomic measurements with subcellular resolution

Photoselective sequencing combines targeted illumination and photocaged fragment libraries to enable the spatial analysis of genomic sequence and chromatin accessibility profiles with subcellular resolution in the context of complex tissues.

Sarah M. Mangiameli
Haiqi Chen
Fei Chen
Research27 Apr 2023
Nature Methods

Volume: 20, P: 686-694
Efficient, continuous mutagenesis in human cells using a pseudo-random DNA editor

Efficient diversification of DNA sequences is enabled by a T7 RNA polymerase fused to a cytidine deaminase.

Haiqi Chen
Sophia Liu
Fei Chen
Research16 Dec 2019
Nature Biotechnology

Volume: 38, P: 165-168

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Photoselective sequencing: microscopically guided genomic measurements with subcellular resolution

Efficient, continuous mutagenesis in human cells using a pseudo-random DNA editor

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