Life-science research and biomedical diagnostics call for robust fluorescence barcodes of compact size and high multiplexing capability. Here DNA-origami technology was used to construct a new kind of geometrically encoded barcode with excellent structural stiffness. They hold promise for both in situ and ex situ imaging of diverse biologically relevant entities.
- Chenxiang Lin
- Ralf Jungmann
- Peng Yin