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Showing 1–4 of 4 results
Advanced filters: Author: Daniel Malzl Clear advanced filters

  • Here the authors show that in activated B cells, RIF1 primarily binds early-replicating active chromatin and promotes early replication. RIF1 and MCM proteins establish early replication timing signatures genome-wide and ensure early replication of highly transcribed genes.

    • Daniel Malzl
    • Mihaela Peycheva
    • Rushad Pavri
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Lindenhofer, Haendeler, Esk, Littleboy et al. perform whole-tissue lineage tracing in human cerebral organoids to reveal that a subpopulation of symmetrically dividing cells can adjust its lineage size depending on tissue demands.

    • Dominik Lindenhofer
    • Simon Haendeler
    • Jürgen A. Knoblich
    ResearchOpen Access
    Nature Cell Biology
    Volume: 26, P: 710-718

  • The glycome of parasites can have immunomodulatory properties or help to avoid immune surveillance, but details are unknown. Here, Martini et al. characterize the N-glycome of the canine heartworm, reveal an unprecedented complexity, particularly in anionic N-glycans, and determine recognition by components of the immune system.

    • Francesca Martini
    • Barbara Eckmair
    • Katharina Paschinger
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-18