Various factors associate with the ribosome to assist in initiation, elongation and termination of translation. Only two universal factors for elongation have previously been identified; here, a factor previously thought to be associated with the initiation process, eIF5A, and which contains a rare amino acid, hypusine, is found to have a central role in elongation.
- Preeti Saini
- Daniel E. Eyler
- Thomas E. Dever
