Triple-negative breast cancers are aggressive tumours, but their prognosis is critically determined by the immune cell activity within the microenvironment, with the more inflamed, hot milieu predicting better prognosis. Here authors show that the tumour draining lymph nodes, even if not invaded by the tumours, reflect the difference between the cold and hot tumours via differential Th2 polarization.
- Weihua Guo
- Jiayi Tan
- Peter P. Lee
