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Showing 1–3 of 3 results
Advanced filters: Author: Danielle Hedeen Clear advanced filters

  • The ability to visualise stochastic invasion events is limited in murine models of metastatic cancers. Here the authors use a transparent zebrafish epidermis model to follow the invasion events of K-Ras transformed epithelial cells and show that these cells invade through basal cell extrusion.

    • John Fadul
    • Teresa Zulueta-Coarasa
    • Jody Rosenblatt
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • Happ et al. uncover an unusual regulatory mechanism in the Hedgehog signaling pathway, which enables a G protein-coupled receptor to physically block the enzymatic activity of a major cellular kinase.

    • John T. Happ
    • Corvin D. Arveseth
    • Benjamin R. Myers
    Research
    Nature Structural & Molecular Biology
    Volume: 29, P: 990-999