microRNAs inhibit mRNA translation and are implicated in modulating synaptic plasticity. Here, Hu et al.show that miR-191 and miR-135 regulate the expression of tropomodulin 2 and complexin-1/2 to produce dendritic spine remodelling, which is associated with synaptic long-term depression.
- Zhonghua Hu
- Danni Yu
- Zheng Li
