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Showing 1–14 of 14 results
Advanced filters: Author: Daohong Song Clear advanced filters

  • Artificial photonic graphene, a honeycomb array of evanescently coupled waveguides, has proven to be a useful tool for investigating graphene physics in various optical settings. Here, Song et al.demonstrate pseudospin-mediated vortex generation and topological charge flipping in otherwise uniform optical beams.

    • Daohong Song
    • Vassilis Paltoglou
    • Zhigang Chen
    Research
    Nature Communications
    Volume: 6, P: 1-7

  • The propagation of light in photonic crystals with a honeycomb structure mirrors the behaviour of charges in graphene, therefore allowing for the investigation of electronic properties that cannot otherwise be accessed in graphene itself. This approach is now used to predict unexpected edge states that localize in the bearded edges of hexagonal lattices.

    • Yonatan Plotnik
    • Mikael C. Rechtsman
    • Mordechai Segev
    Research
    Nature Materials
    Volume: 13, P: 57-62

  • Senolytics have the potential to extend healthspan by selectively killing senescent cells (SCs), but senolytics that target Bcl-xl may cause platelet toxicity. Here, the authors generated a Bcl-xl proteolysis-targeting chimera (PROTAC) senolytic, which effectively clears SCs and rejuvenates tissue stem and progenitor cells in naturally aged mice without causing severe thrombocytopenia.

    • Yonghan He
    • Xuan Zhang
    • Daohong Zhou
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • Targeting regulatory T cells (Treg) represents a therapeutic option to abrogate tumor-associated immune suppression. Here the authors show that pharmacological degradation of BCL-XL preferentially induces apoptosis of tumor-infiltrating Treg, promoting CD8 T cell activation and anti-tumor immune responses in preclinical cancer models.

    • Ryan Kolb
    • Umasankar De
    • Weizhou Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • Topological protection in disclination lattices that relies on non-trivial winding in momentum space and real space is used to confine and guide vortices that feature arbitrary high-order charges. This approach could help in the development of orbital angular momentum-based photonic devices.

    • Zhichan Hu
    • Domenico Bongiovanni
    • Zhigang Chen
    ResearchOpen Access
    Nature Photonics
    Volume: 19, P: 162-169

  • Controlled generation of OAM modes holds promise for applications in classical and quantum communication networks. Here the authors develop an optical vortex ladder in which an input beam transforms into vortices mediated by the Berry phase winding around topological singularities at the Dirac points.

    • Sihong Lei
    • Shiqi Xia
    • Zhigang Chen
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9

  • Some topological boundary states are symmetry protected. Experiments with photonic lattices now show that the protection via sub-symmetry is enough to ensure topological modes, even if the full symmetry and topological invariant are destroyed.

    • Ziteng Wang
    • Xiangdong Wang
    • Hrvoje Buljan
    ResearchOpen Access
    Nature Physics
    Volume: 19, P: 992-998

  • Regulatory T (Treg) cells are important modulators of the tumor microenvironment. Here the authors perform transcriptome profiling of immune cells from patients with renal clear cell carcinoma to find a Treg signature that correlates with poorer prognosis, with CD177 being implicated as the main mediator for related alterations in Treg activity and tumor outcome.

    • Myung-Chul Kim
    • Nicholas Borcherding
    • Weizhou Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13

  • Topological properties of materials are typically presented in momentum space. Here, the authors show a universal mapping of topological singularities from momentum to real space, potentially applicable to a wide range of systems.

    • Xiuying Liu
    • Shiqi Xia
    • Zhigang Chen
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8