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Advanced filters: Author: Darrix Lim Clear advanced filters

  • Peripherally restricted CB1 inhibitors retain the weight loss benefits of this drug class while sparing the negative psychiatric side effects. The authors here elucidate cryo-EM structures of CB1 bound to peripherally restricted inhibitors to explain these drugs’ molecular mechanism of action.

    • Punita Kumari
    • Szabolcs Dvorácskó
    • Daniel M. Rosenbaum
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13