Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Daseuli Yu Clear advanced filters

  • Spatiotemporal control of biomolecules is a key challenge in cell biology. Here, authors introduce RELISR, an optogenetic condensate system enabling reversible, light-dependent sequestration and release of proteins or mRNA in cells and live animals.

    • Chaeyeon Lee
    • Jeonghye Yu
    • Won Do Heo
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Cas13 systems suffer from a lack of spatiotemporal control. Here the authors report paCas13, a light-inducible Cas13 system created by fusing Magnet with fragment pairs; they also report padCas13, a light-inducible base-editing system by fusing ADAR2 to catalytically inactive paCas13 fragments.

    • Jeonghye Yu
    • Jongpil Shin
    • Won Do Heo
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Armfield X-linked disability (XLID) disorder has previously been linked to a locus in Xq28. Here, the authors report rare missense variants in FAM50A at Xq28, show that FAM50A interacts with the spliceosome, and that mis-splicing is enriched in knockout zebrafish suggesting it is a spliceosomopathy.

    • Yu-Ri Lee
    • Kamal Khan
    • Charles E. Schwartz
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-17

  • Most approaches to control gene expression in vivo require generation of knock-in mouse lines and often lack spatiotemporal control. Here the authors develop a photo-activatable Flp recombinase system and demonstrate its use by controlling object-exploration behavior in mice through Cav3.1 silencing.

    • Hyunjin Jung
    • Seong-Wook Kim
    • Won Do Heo
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10