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Showing 1–5 of 5 results
Advanced filters: Author: Daven Vasishtan Clear advanced filters

  • Visualizing the stages of herpesvirus nuclear egress in situ using cryoET and subvolume averaging shows how nascent virions pass through the nuclear membrane.

    • Vojtěch Pražák
    • Yuliia Mironova
    • Kay Grünewald
    Research
    Nature Microbiology
    Volume: 9, P: 1842-1855

  • The authors employ cryo-ET to study the structure of the palisade layer of the mature vaccinia virus core in isolation, as well as inside infected cells, revealing that it is composed of A10 protein trimers.

    • Jiasui Liu
    • Simon Corroyer-Dulmont
    • Jacomina Krijnse Locker
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 31, P: 1105-1113

  • Microtubules are a ubiquitous eukaryotic cytoskeletal element typically consisting of 13 protofilaments arranged in a hollow cylinder. Using CryoEM and subvolume averaging, Ferreira and Pražák et al. show that Plasmodium does not adhere to a single microtubule structure. Instead, the cytoskeleton changes substantially to produce a unique, fit for purpose structure and organisation at each stage of its life cycle.

    • Josie L. Ferreira
    • Vojtěch Pražák
    • Kay Grünewald
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Cell–cell fusion in Caenorhabditis elegans is mediated by EFF-1 and AFF-1 proteins. Here, the authors present an electron cryomicroscopy 3D reconstruction of EFF-1 in the membrane, and combine snapshots of membrane fusion in vitrowith a recently reported crystal structure to propose a mechanism for the fusion process.

    • Tzviya Zeev-Ben-Mordehai
    • Daven Vasishtan
    • Kay Grünewald
    ResearchOpen Access
    Nature Communications
    Volume: 5, P: 1-9