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Showing 1–40 of 40 results
Advanced filters: Author: David Goodstein Clear advanced filters
    • David Goodstein
    • Judith Goodstein
    Books & Arts
    Nature
    Volume: 380, P: 300
  • What makes a scientist deceive? Faked data, fudged numbers, filched ideas: how common in science are these grave sins? There may only be a handful of cases where scientists managed to fool the whole world—a Jon Hendrik Schön here, a Woo-Suk Hwang there—but survey after survey reveals that your garden-variety fraud is more prevalent than anyone cares to admit. Whose responsibility is it to police misconduct in science? And what motivates it in the first place? In the following pages, we take a look at what prompts those ethical missteps and what governments, universities, journals—and you—can do about it.

    • David Cyranoski
    News
    Nature Medicine
    Volume: 12, P: 490
  • Phaeocystales are ecologically significant nanoplankton whose evolutionary history and functional diversity remain incompletely characterized. Here, the authors integrate genomic and transcriptomic data to reveal their lineage diversification, metabolic plasticity, and adaptation to polar and temperate regimes.

    • Zoltán Füssy
    • Robert H. Lampe
    • Andrew E. Allen
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18
    • David Goodstein
    • Frank J. Gilloon
    Comments & Opinion
    Bio/Technology
    Volume: 13, P: 618
    • David Goodstein
    • Judith Goodstein
    Comments & Opinion
    Nature
    Volume: 389, P: 146
  • Soybean is an important crop plant, providing seed protein and oil and fixing atmospheric nitrogen through symbioses with soil-borne microorganisms. Using a whole-genome shotgun approach, its 1.1-gigabase genome is now sequenced and integrated with physical and high-density genetic maps to create a chromosome-scale draft sequence assembly.

    • Jeremy Schmutz
    • Steven B. Cannon
    • Scott A. Jackson
    ResearchOpen Access
    Nature
    Volume: 463, P: 178-183
    • David Goodstein
    Comments & Opinion
    Nature Physics
    Volume: 3, P: 585
    • David Goodstein
    Comments & Opinion
    Nature Physics
    Volume: 3, P: 291
    • David Goodstein
    Comments & Opinion
    Nature Physics
    Volume: 3, P: 439
    • David Goodstein
    Comments & Opinion
    Nature Physics
    Volume: 3, P: 141
    • David Goodstein
    Comments & Opinion
    Nature Physics
    Volume: 3, P: 673
    • David Goodstein
    Comments & Opinion
    Nature Physics
    Volume: 3, P: 73
  • Oaks can live hundreds of years. Comparative genomics using a high-quality genome sequence provides new insights that may explain tree longevity. Samples from branches and corresponding acorns also help quantify heritable somatic mutations.

    • Christophe Plomion
    • Jean-Marc Aury
    • Jérôme Salse
    ResearchOpen Access
    Nature Plants
    Volume: 4, P: 440-452
  • Meditope-Fab is a peptide-antibody complex potentially useful for drug delivery and diagnostic, but a short half-life prevents its use in vivo. Here the authors engineer the complex to improve its stability, create functionalized antibodies by click chemistry and use them for in vivo tumor imaging.

    • Krzysztof P. Bzymek
    • James W. Puckett
    • John C. Williams
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9
  • While greater yam provides food and income security for millions of people around the world, there are limited genomic resources available. Here, the authors report a chromosome-scale assembly of the greater yam genome as well as quantitative trait loci associated with anthracnose resistance and tuber traits.

    • Jessen V. Bredeson
    • Jessica B. Lyons
    • Daniel S. Rokhsar
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16
  • These authors report and analyse the draft genome sequence of the demosponge Amphimedon queenslandica. Sponges lie on the earliest branching lineage in the animal kingdom and thus have been important in studies of the origins of multicellularity. Comparative genomic analyses presented here provide significant insights into evolutionary origins of genes and pathways related to the hallmarks of metazoan multicellularity and to cancer biology.

    • Mansi Srivastava
    • Oleg Simakov
    • Daniel S. Rokhsar
    ResearchOpen Access
    Nature
    Volume: 466, P: 720-726
  • The International Peach Genome Initiative reports the high quality draft genome sequence of peach (Prunus persica). They also resequenced ten additional P. persica accessions, as well as those of Prunus ferganensis, Prunus kansuensis, Prunus davidiana and Prunus mira.

    • Ignazio Verde
    • Albert G Abbott
    • Daniel S Rokhsar
    ResearchOpen Access
    Nature Genetics
    Volume: 45, P: 487-494
  • The Eucalyptus grandis genome has been sequenced, revealing the greatest number of tandem duplications of any plant genome sequenced so far, and the highest diversity of genes for specialized metabolites that act as chemical defence and provide unique pharmaceutical oils; genome sequencing of the sister species E. globulus and a set of inbred E. grandis tree genomes reveals dynamic genome evolution and hotspots of inbreeding depression.

    • Alexander A. Myburg
    • Dario Grattapaglia
    • Jeremy Schmutz
    ResearchOpen Access
    Nature
    Volume: 510, P: 356-362
  • The role of differential gene content in the evolution and function of eukaryotic genomes remains poorly explored. Here the authors assemble and annotate the Brachypodium distachyon pan-genome consisting of 54 diverse lines and reveal the differential present genes as a major driver of phenotypic variation.

    • Sean P. Gordon
    • Bruno Contreras-Moreira
    • John P. Vogel
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-13
  • Scott Jackson, Jeremy Schmutz, Phillip McClean and colleagues report the genome sequence of the common bean (Phaseolus vulgaris) and resequenced wild individuals and landraces from Mesoamerican and Andean gene pools, showing that common bean underwent two independent domestications.

    • Jeremy Schmutz
    • Phillip E McClean
    • Scott A Jackson
    ResearchOpen Access
    Nature Genetics
    Volume: 46, P: 707-713
  • Existing plant pan-genomic studies usually report considerable intraspecific whole gene presence-absence variation. Here, the authors use pan-genomic approach to reveal gradual polyploid genome evolution by analyzing of Brachypodium hybridum and its diploid progenitors.

    • Sean P. Gordon
    • Bruno Contreras-Moreira
    • John P. Vogel
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16
  • Crassulacean acid metabolism (CAM) is a metabolic adaptation of photosynthesis that enhances water use efficiency. Here, via genomic analysis of Kalanchoë, the authors provide evidence for convergent evolution of protein sequence and temporal gene expression underpinning the multiple independent emergences of CAM.

    • Xiaohan Yang
    • Rongbin Hu
    • Gerald A. Tuskan
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15
  • Analyses of three newly sequenced modern cultivar cotton genomes revealed sequence and structural variation alongside traces of ancient and ongoing introgressions. Moreover, transcriptome analysis pointed at unique fibre quality traits of cultivars.

    • Avinash Sreedasyam
    • John T. Lovell
    • Jeremy Schmutz
    ResearchOpen Access
    Nature Plants
    Volume: 10, P: 1039-1051
  • The freshwater cnidarian Hydra is a significant model for studies of axial patterning, stem cell biology and regeneration. Its (A+T)-rich genome has now been sequenced. Comparison of this genome with those of other animals provides insights into the evolution of epithelia, contractile tissues, developmentally regulated transcription factors, pluripotency genes and more.

    • Jarrod A. Chapman
    • Ewen F. Kirkness
    • Robert E. Steele
    ResearchOpen Access
    Nature
    Volume: 464, P: 592-596