Nature Search

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

Marina Cella
David Jarrossay
Marco Colonna
Research01 Aug 1999
Nature Medicine

Volume: 5, P: 919-923
Immune response: steroids drive dendritic cells

The newly identified steroid ligand of the receptor EBI2 (GPCR183), 7α,25-dihydroxycholesterol, is required for the positioning of splenic CD4⁺ dendritic cells in bridging channels to prime T cells for an efficient antibody response.

David Jarrossay
Marcus Thelen
News & Views18 Apr 2013
Nature Immunology

Volume: 14, P: 424-426
Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition

Tumor-associated neutrophils exhibit heterogeneity in breast cancer. Here, the authors identify a distinct precursor population (PreNeu) in estrogen receptor-positive tumors. PreNeu suppress homologous recombination in cancer cells, promoting error-prone DNA repair and enhancing sensitivity to PARP inhibitors.

Siddhartha Mukherjee
Cindy Garda
Arianna Calcinotto
ResearchOpen Access30 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human T_H17 cells

Dominik Aschenbrenner
Mathilde Foglierini
Federica Sallusto
Amendments and Corrections17 Nov 2018
Nature Immunology

Volume: 20, P: 109
An immunoregulatory and tissue-residency program modulated by c-MAF in human T_H17 cells

T_H17 cells contribute to anti-fungal and anti-bacterial adaptive immune responses. Sallusto and colleagues show that the transcription factor c-Maf has an immunoregulatory role in directing gene expression and tissue residency in human IL-10⁺ T_H17 cell subsets.

Dominik Aschenbrenner
Mathilde Foglierini
Federica Sallusto
Research10 Sept 2018
Nature Immunology

Volume: 19, P: 1126-1136
T cells in patients with narcolepsy target self-antigens of hypocretin neurons

The detection of hypocretin-specific autoreactive CD4⁺ and CD8⁺ T cells in patients with narcolepsy reveals the autoimmune aetiology of this disorder.

Daniela Latorre
Ulf Kallweit
Federica Sallusto
Research19 Sept 2018
Nature

Volume: 562, P: 63-68
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

Helper T cells become polarized to effect a 'division of labor'. Sallusto and Spits and colleagues identify a new subset of skin-homing helper T cells, T_H-22 cells, that secrete interleukin 22.

Thomas Duhen
Rebekka Geiger
Federica Sallusto
Research05 Jul 2009
Nature Immunology

Volume: 10, P: 857-863
Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

Eva V Acosta-Rodriguez
Laura Rivino
Giorgio Napolitani
Research07 May 2007
Nature Immunology

Volume: 8, P: 639-646
Identification of clonogenic common Flt3⁺M-CSFR⁺ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow

Nobuyuki Onai
Aya Obata-Onai
Markus G Manz
Research07 Oct 2007
Nature Immunology

Volume: 8, P: 1207-1216
Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course

Robbiani and colleagues show that antibodies against specific chemokines are detected in COVID-19 convalescents and may modulate the inflammatory response and disease outcome.

Jonathan Muri
Valentina Cecchinato
Davide F. Robbiani
ResearchOpen Access06 Mar 2023
Nature Immunology

Volume: 24, P: 604-611
A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients

An analysis of T cell specificities sufficient to sustain a neutralizing anti-drug antibody response offers a potential approach for enhancing the clinical efficacy of a therapeutic humanized antibody.

Antonino Cassotta
Vincent Mikol
Luca Piccoli
Research09 Sept 2019
Nature Medicine

Volume: 25, P: 1402-1407
Pathogen-induced human T_H17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

Infection with Candida albicans and Staphylococcus aureus gives rise to T_H17 cells with different properties; microbe-induced T-cell differentiation is shown here to depend on the balance between polarizing cytokines rather than absolute amounts.

Christina E. Zielinski
Federico Mele
Federica Sallusto
Research01 Apr 2012
Nature

Volume: 484, P: 514-518
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

Monoclonal antibodies with broad reactivity against antigens on the parasite that causes malaria, Plasmodium falciparum, are isolated from two subjects and are found to have an unusual insertion of an immunoglobulin-like domain from a different chromosome, illustrating a new mechanism of antibody diversification.

Joshua Tan
Kathrin Pieper
Antonio Lanzavecchia
Research23 Dec 2015
Nature

Volume: 529, P: 105-109
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities

Up to 10% of individuals in malaria-endemic regions produce antibodies that react to malaria antigens through an additional LAIR1 domain that is inserted by two different insertion modalities.

Kathrin Pieper
Joshua Tan
Antonio Lanzavecchia
Research23 Aug 2017
Nature

Volume: 548, P: 597-601
Social network architecture of human immune cells unveiled by quantitative proteomics

Immune cells give rise to the most interconnected system in the body. Meissner and colleagues perform comprehensive proteomics and secretomics to describe in detail the ‘social network’ of human immune cells and throw light on previously unknown cell connectivities.

Jan C Rieckmann
Roger Geiger
Felix Meissner
Research06 Mar 2017
Nature Immunology

Volume: 18, P: 583-593

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Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

Immune response: steroids drive dendritic cells

Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition

Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human T_H17 cells

An immunoregulatory and tissue-residency program modulated by c-MAF in human T_H17 cells

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

Identification of clonogenic common Flt3⁺M-CSFR⁺ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow

Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course

A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients

Pathogen-induced human T_H17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities

Social network architecture of human immune cells unveiled by quantitative proteomics

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