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Showing 1–22 of 22 results
Advanced filters: Author: David L. Egholm Clear advanced filters
  • Wastewater-based surveillance tends to focus on specific pathogens. Here, the authors mapped the wastewater virome from 62 cities worldwide to identify over 2,500 viruses, revealing city-specific virome fingerprints and showing that wastewater metagenomics enables early detection of emerging viruses.

    • Nathalie Worp
    • David F. Nieuwenhuijse
    • Miranda de Graaf
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19
  • Previously glaciated landscapes tend to have large areas concentrated at the same elevation; here it is shown that small climate changes can trigger massive glacial expansions for these landscapes, explaining long-term patterns of erosion in the Quaternary period.

    • Vivi Kathrine Pedersen
    • David Lundbek Egholm
    Research
    Nature
    Volume: 493, P: 206-210
  • The goal of the 1000 Genomes Project is to provide in-depth information on variation in human genome sequences. In the pilot phase reported here, different strategies for genome-wide sequencing, using high-throughput sequencing platforms, were developed and compared. The resulting data set includes more than 95% of the currently accessible variants found in any individual, and can be used to inform association and functional studies.

    • Richard M. Durbin
    • David Altshuler (Co-Chair)
    • Gil A. McVean
    ResearchOpen Access
    Nature
    Volume: 467, P: 1061-1073
  • The relative importance of the various factors that lead to intraplate deformation has been difficult to establish. Modelling results show that compressional deformation of a thick sedimentary basin in southeastern Ukraine was facilitated by strain localization resulting from the contrast in thermal conductivity between the basin and the surrounding crystalline crust.

    • Randell Stephenson
    • David L. Egholm
    • Sergiy M. Stovba
    Research
    Nature Geoscience
    Volume: 2, P: 290-293
  • For half a century, the cause for recent uplift of the European Alps has been debated. Here, the authors show that ∼90% of the geodetically measured rock uplift in the Alps can be explained by the Earth’s viscoelastic response to ice melting after the Last Glacial Maximum.

    • Jürgen Mey
    • Dirk Scherler
    • Manfred R. Strecker
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-10
  • Erosion rates and ice cover extent of present day fjords and summit plateau landscapes beyond the last deglaciation are virtually unknown. Here, the authors constrain the long-term denudation rates and glaciation history in west Greenland based on cosmogenic nuclides.

    • Astrid Strunk
    • Mads Faurschou Knudsen
    • Nicolaj K. Larsen
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-8
  • Plateaus separated by deeply incised fjords are hallmarks of glaciated passive continental margins. Computational experiments show that they arise from evolving feedbacks between topography, ice dynamics and erosion over millions of years.

    • David L. Egholm
    • John D. Jansen
    • Mads F. Knudsen
    Research
    Nature Geoscience
    Volume: 10, P: 592-597
  • The assessment of soil sustainability in prehistoric times requires comparing millennium-scale erosion rates with geological background rates. Here, the authors apply in situ cosmogenic 14C, 10Be, and 26Al to reveal rapid soil erosion on the Andean Altiplano in response to Late Holocene climate change and the onset of agropastoralism.

    • Kristina Hippe
    • John D. Jansen
    • David Lundbek Egholm
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9
  • The contribution of surface processes to the long-term evolution of plateau surfaces on high-latitude passive margins is poorly understood. Here, the authors show that recent glacial erosion on plateaus in western Scandinavia was widespread and may have contributed substantially to the sediment flux to the oceans.

    • Jane L. Andersen
    • David L. Egholm
    • Sheng Xu
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-7
  • There are indications that the general height of mountain ranges is directly influenced by the extent of glaciation through an efficient denudation mechanism known as the glacial buzzsaw. Here, a global analysis of topography shows that variations in maximum mountain height correlate closely with climate-controlled gradients in snowline altitude rather than with tectonic activity. Further, the use of a numerical model self-consistently produces the hypsometric signature of the glacial buzzsaw.

    • D. L. Egholm
    • S. B. Nielsen
    • J.-E. Lesemann
    Research
    Nature
    Volume: 460, P: 884-887
  • Riccardo Velasco and colleagues report the genome sequence of the 'Golden Delicious' domesticated apple. These data shed new insight into the genomic events that preceded the origin of this crop.

    • Riccardo Velasco
    • Andrey Zharkikh
    • Roberto Viola
    Research
    Nature Genetics
    Volume: 42, P: 833-839
  • The DNA sequence of a diploid genome of a single individual, James D. Watson, sequenced to 7.4-fold redundancy in two months using massively parallel sequencing in picolitre-size reaction vessels is reported.

    • David A. Wheeler
    • Maithreyan Srinivasan
    • Jonathan M. Rothberg
    ResearchOpen Access
    Nature
    Volume: 452, P: 872-876
  • This paper reports the genome sequence of domesticated tomato, a major crop plant, and a draft sequence for its closest wild relative; comparative genomics reveal very little divergence between the two genomes but some important differences with the potato genome, another important food crop in the genus Solanum.

    • Shusei Sato
    • Satoshi Tabata
    • René M. Klein Lankhorst
    ResearchOpen Access
    Nature
    Volume: 485, P: 635-641