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Showing 1–7 of 7 results

Advanced filters: Author: David Marcellin Clear advanced filters

Development of a p62 biodegrader for autophagy targeted degradation

Using proximity-based screening, protein engineering, and structural analysis, this study describes the development of a p62-based biodegrader for the clearance of organelles and aggregated proteins by autophagy-targeted degradation.

Zacharias Thiel
David Marcellin
Beat Nyfeler
ResearchOpen Access03 Dec 2025
Nature Communications

Volume: 16, P: 1-18
Japan seeks to reverse drop in interest in science

David Swinbanks
News17 Mar 1994
Nature

Volume: 368, P: 181
Insights into the accuracy of social scientists’ forecasts of societal change

How accurate are social scientists in predicting societal change, and what processes underlie their predictions? Grossmann et al. report the findings of two forecasting tournaments. Social scientists’ forecasts were on average no more accurate than those of simple statistical models.

Igor Grossmann
Amanda Rotella
Tom Wilkening
Research09 Feb 2023
Nature Human Behaviour

Volume: 7, P: 484-501
sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial

David M. Smadja
Clément R. Massonnaud
Benjamin Leveau
ResearchOpen Access24 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
HaloPROTAC3 does not trigger the degradation of the halotagged parasitophorous vacuole membrane protein UIS4 during Plasmodium liver stage development

Melanie Lam
Alexandra Probst
Gabriel Mitchell
ResearchOpen Access26 May 2025
Scientific Reports

Volume: 15, P: 1-16
Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo

Oliver M. Russell
Isabelle Fruh
Stephen B. Helliwell
ResearchOpen Access29 Jan 2018
Scientific Reports

Volume: 8, P: 1-10
Chk1 KA1 domain auto-phosphorylation stimulates biological activity and is linked to rapid proteasomal degradation

Eun-Yeung Gong
Beatriz Hernández
David A. Gillespie
ResearchOpen Access03 Dec 2018
Scientific Reports

Volume: 8, P: 1-11